FDXR

Ferredoxin reductase, also known as FDXR, is a human gene.cite web | title = Entrez Gene: FDXR ferredoxin reductase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2232| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants of this gene have been described although the full-length nature of only two that encode different isoforms have been determined.cite web | title = Entrez Gene: FDXR ferredoxin reductase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2232| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Sparkes RS, Klisak I, Miller WL |title=Regional mapping of genes encoding human steroidogenic enzymes: P450scc to 15q23-q24, adrenodoxin to 11q22; adrenodoxin reductase to 17q24-q25; and P450c17 to 10q24-q25. |journal=DNA Cell Biol. |volume=10 |issue= 5 |pages= 359–65 |year= 1991 |pmid= 1863359 |doi=
*cite journal | author=Coghlan VM, Vickery LE |title=Site-specific mutations in human ferredoxin that affect binding to ferredoxin reductase and cytochrome P450scc. |journal=J. Biol. Chem. |volume=266 |issue= 28 |pages= 18606–12 |year= 1991 |pmid= 1917982 |doi=
*cite journal | author=Lin D, Shi YF, Miller WL |title=Cloning and sequence of the human adrenodoxin reductase gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 21 |pages= 8516–20 |year= 1990 |pmid= 2236061 |doi=
*cite journal | author=Usanov SA, Chernogolov AA, Honkakoski P, "et al." |title= [Cholesterol-hydroxylating cytochrome P-450 from bovine adrenal cortex mitochondria and human placenta: immunochemical properties and structural characteristics] |journal=Biokhimiia |volume=55 |issue= 5 |pages= 865–77 |year= 1990 |pmid= 2393675 |doi=
*cite journal | author=Sasano H, Sasano N, Okamoto M, Nonaka Y |title=Immunohistochemical demonstration of adrenodoxin reductase in bovine and human adrenals. |journal=Pathol. Res. Pract. |volume=184 |issue= 5 |pages= 473–9 |year= 1989 |pmid= 2748461 |doi=
*cite journal | author=Usanov SA, Honkakoski P, Lang MA, "et al." |title=Comparison of the immunochemical properties of human placental and bovine adrenal cholesterol side-chain cleavage enzyme complex. |journal=Biochim. Biophys. Acta |volume=998 |issue= 2 |pages= 189–95 |year= 1989 |pmid= 2790061 |doi=
*cite journal | author=Solish SB, Picado-Leonard J, Morel Y, "et al." |title=Human adrenodoxin reductase: two mRNAs encoded by a single gene on chromosome 17cen----q25 are expressed in steroidogenic tissues. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 19 |pages= 7104–8 |year= 1988 |pmid= 2845396 |doi=
*cite journal | author=Mittal S, Zhu YZ, Vickery LE |title=Molecular cloning and sequence analysis of human placental ferredoxin. |journal=Arch. Biochem. Biophys. |volume=264 |issue= 2 |pages= 383–91 |year= 1988 |pmid= 2969697 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Müller JJ, Lapko A, Bourenkov G, "et al." |title=Adrenodoxin reductase-adrenodoxin complex structure suggests electron transfer path in steroid biosynthesis. |journal=J. Biol. Chem. |volume=276 |issue= 4 |pages= 2786–9 |year= 2001 |pmid= 11053423 |doi= 10.1074/jbc.M008501200
*cite journal | author=Gonzalez MI, Robins DM |title=Oct-1 preferentially interacts with androgen receptor in a DNA-dependent manner that facilitates recruitment of SRC-1. |journal=J. Biol. Chem. |volume=276 |issue= 9 |pages= 6420–8 |year= 2001 |pmid= 11096094 |doi= 10.1074/jbc.M008689200
*cite journal | author=Tuckey RC, Headlam MJ |title=Placental cytochrome P450scc (CYP11A1): comparison of catalytic properties between conditions of limiting and saturating adrenodoxin reductase. |journal=J. Steroid Biochem. Mol. Biol. |volume=81 |issue= 2 |pages= 153–8 |year= 2002 |pmid= 12137805 |doi=
*cite journal | author=Liu G, Chen X |title=The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis. |journal=Oncogene |volume=21 |issue= 47 |pages= 7195–204 |year= 2002 |pmid= 12370809 |doi= 10.1038/sj.onc.1205862
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Araya Z, Hosseinpour F, Bodin K, Wikvall K |title=Metabolism of 25-hydroxyvitamin D3 by microsomal and mitochondrial vitamin D3 25-hydroxylases (CYP2D25 and CYP27A1): a novel reaction by CYP27A1. |journal=Biochim. Biophys. Acta |volume=1632 |issue= 1-3 |pages= 40–7 |year= 2003 |pmid= 12782149 |doi=
*cite journal | author=Thiboutot D, Jabara S, McAllister JM, "et al." |title=Human skin is a steroidogenic tissue: steroidogenic enzymes and cofactors are expressed in epidermis, normal sebocytes, and an immortalized sebocyte cell line (SEB-1). |journal=J. Invest. Dermatol. |volume=120 |issue= 6 |pages= 905–14 |year= 2003 |pmid= 12787114 |doi= 10.1046/j.1523-1747.2003.12244.x
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406

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