Peroxisomal biogenesis factor 14, also known as PEX14, is a human gene.cite web | title = Entrez Gene: PEX14 peroxisomal biogenesis factor 14| url =| accessdate = ]

section_title =
summary_text = This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.cite web | title = Entrez Gene: PEX14 peroxisomal biogenesis factor 14| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Albertini M, Rehling P, Erdmann R, "et al." |title=Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways. |journal=Cell |volume=89 |issue= 1 |pages= 83–92 |year= 1997 |pmid= 9094717 |doi=
*cite journal | author=Huhse B, Rehling P, Albertini M, "et al." |title=Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery. |journal=J. Cell Biol. |volume=140 |issue= 1 |pages= 49–60 |year= 1998 |pmid= 9425153 |doi=
*cite journal | author=Fransen M, Terlecky SR, Subramani S |title=Identification of a human PTS1 receptor docking protein directly required for peroxisomal protein import. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 14 |pages= 8087–92 |year= 1998 |pmid= 9653144 |doi=
*cite journal | author=Will GK, Soukupova M, Hong X, "et al." |title=Identification and characterization of the human orthologue of yeast Pex14p. |journal=Mol. Cell. Biol. |volume=19 |issue= 3 |pages= 2265–77 |year= 1999 |pmid= 10022913 |doi=
*cite journal | author=Girzalsky W, Rehling P, Stein K, "et al." |title=Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes. |journal=J. Cell Biol. |volume=144 |issue= 6 |pages= 1151–62 |year= 1999 |pmid= 10087260 |doi=
*cite journal | author=Shimizu N, Itoh R, Hirono Y, "et al." |title=The peroxin Pex14p. cDNA cloning by functional complementation on a Chinese hamster ovary cell mutant, characterization, and functional analysis. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12593–604 |year= 1999 |pmid= 10212238 |doi=
*cite journal | author=Sacksteder KA, Jones JM, South ST, "et al." |title=PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. |journal=J. Cell Biol. |volume=148 |issue= 5 |pages= 931–44 |year= 2000 |pmid= 10704444 |doi=
*cite journal | author=Gavva NR, Wen SC, Daftari P, "et al." |title=NAPP2, a peroxisomal membrane protein, is also a transcriptional corepressor. |journal=Genomics |volume=79 |issue= 3 |pages= 423–31 |year= 2002 |pmid= 11863372 |doi= 10.1006/geno.2002.6714
*cite journal | author=Otera H, Setoguchi K, Hamasaki M, "et al." |title=Peroxisomal targeting signal receptor Pex5p interacts with cargoes and import machinery components in a spatiotemporally differentiated manner: conserved Pex5p WXXXF/Y motifs are critical for matrix protein import. |journal=Mol. Cell. Biol. |volume=22 |issue= 6 |pages= 1639–55 |year= 2002 |pmid= 11865044 |doi=
*cite journal | author=Alland L, David G, Shen-Li H, "et al." |title=Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex. |journal=Mol. Cell. Biol. |volume=22 |issue= 8 |pages= 2743–50 |year= 2002 |pmid= 11909966 |doi=
*cite journal | author=Fransen M, Brees C, Ghys K, "et al." |title=Analysis of mammalian peroxin interactions using a non-transcription-based bacterial two-hybrid assay. |journal=Mol. Cell Proteomics |volume=1 |issue= 3 |pages= 243–52 |year= 2002 |pmid= 12096124 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Oliveira ME, Reguenga C, Gouveia AM, "et al." |title=Mammalian Pex14p: membrane topology and characterisation of the Pex14p-Pex14p interaction. |journal=Biochim. Biophys. Acta |volume=1567 |issue= 1-2 |pages= 13–22 |year= 2003 |pmid= 12488033 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Fransen M, Vastiau I, Brees C, "et al." |title=Potential role for Pex19p in assembly of PTS-receptor docking complexes. |journal=J. Biol. Chem. |volume=279 |issue= 13 |pages= 12615–24 |year= 2004 |pmid= 14715663 |doi= 10.1074/jbc.M304941200
*cite journal | author=Shimozawa N, Tsukamoto T, Nagase T, "et al." |title=Identification of a new complementation group of the peroxisome biogenesis disorders and PEX14 as the mutated gene. |journal=Hum. Mutat. |volume=23 |issue= 6 |pages= 552–8 |year= 2004 |pmid= 15146459 |doi= 10.1002/humu.20032
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Nguyen T, Bjorkman J, Paton BC, Crane DI |title=Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance. |journal=J. Cell. Sci. |volume=119 |issue= Pt 4 |pages= 636–45 |year= 2006 |pmid= 16449325 |doi= 10.1242/jcs.02776

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