MAGED1

Melanoma antigen family D, 1, also known as MAGED1, is a human gene.cite web | title = Entrez Gene: MAGED1 melanoma antigen family D, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9500| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.cite web | title = Entrez Gene: MAGED1 melanoma antigen family D, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9500| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Põld M, Zhou J, Chen GL, "et al." |title=Identification of a new, unorthodox member of the MAGE gene family. |journal=Genomics |volume=59 |issue= 2 |pages= 161–7 |year= 1999 |pmid= 10409427 |doi= 10.1006/geno.1999.5870
*cite journal | author=Salehi AH, Roux PP, Kubu CJ, "et al." |title=NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. |journal=Neuron |volume=27 |issue= 2 |pages= 279–88 |year= 2000 |pmid= 10985348 |doi=
*cite journal | author=Masuda Y, Sasaki A, Shibuya H, "et al." |title=Dlxin-1, a novel protein that binds Dlx5 and regulates its transcriptional function. |journal=J. Biol. Chem. |volume=276 |issue= 7 |pages= 5331–8 |year= 2001 |pmid= 11084035 |doi= 10.1074/jbc.M008590200
*cite journal | author=Kubu CJ, Goldhawk DG, Barker PA, Verdi JM |title=Identification of the translational initiation codon in human MAGED1. |journal=Genomics |volume=70 |issue= 1 |pages= 150–2 |year= 2001 |pmid= 11087672 |doi= 10.1006/geno.2000.6356
*cite journal | author=Zhang CG, Xing GC, Wei HD, "et al." |title= [A new melanoma antigen-encoding gene subfamily in human chromosome X] |journal=Yi Chuan Xue Bao |volume=28 |issue= 3 |pages= 197–203 |year= 2001 |pmid= 11280991 |doi=
*cite journal | author=Stone B, Schummer M, Paley PJ, "et al." |title=MAGE-F1, a novel ubiquitously expressed member of the MAGE superfamily. |journal=Gene |volume=267 |issue= 2 |pages= 173–82 |year= 2001 |pmid= 11313144 |doi=
*cite journal | author=Jordan BW, Dinev D, LeMellay V, "et al." |title=Neurotrophin receptor-interacting mage homologue is an inducible inhibitor of apoptosis protein-interacting protein that augments cell death. |journal=J. Biol. Chem. |volume=276 |issue= 43 |pages= 39985–9 |year= 2001 |pmid= 11546791 |doi= 10.1074/jbc.C100171200
*cite journal | author=Sasaki A, Masuda Y, Iwai K, "et al." |title=A RING finger protein Praja1 regulates Dlx5-dependent transcription through its ubiquitin ligase activity for the Dlx/Msx-interacting MAGE/Necdin family protein, Dlxin-1. |journal=J. Biol. Chem. |volume=277 |issue= 25 |pages= 22541–6 |year= 2002 |pmid= 11959851 |doi= 10.1074/jbc.M109728200
*cite journal | author=Xu YC, Wu RF, Gu Y, "et al." |title=Involvement of TRAF4 in oxidative activation of c-Jun N-terminal kinase. |journal=J. Biol. Chem. |volume=277 |issue= 31 |pages= 28051–7 |year= 2002 |pmid= 12023963 |doi= 10.1074/jbc.M202665200
*cite journal | author=Kendall SE, Goldhawk DE, Kubu C, "et al." |title=Expression analysis of a novel p75(NTR) signaling protein, which regulates cell cycle progression and apoptosis. |journal=Mech. Dev. |volume=117 |issue= 1-2 |pages= 187–200 |year= 2003 |pmid= 12204258 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Williams ME, Strickland P, Watanabe K, Hinck L |title=UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE. |journal=J. Biol. Chem. |volume=278 |issue= 19 |pages= 17483–90 |year= 2003 |pmid= 12598531 |doi= 10.1074/jbc.M300415200
*cite journal | author=Matsuda T, Suzuki H, Oishi I, "et al." |title=The receptor tyrosine kinase Ror2 associates with the melanoma-associated antigen (MAGE) family protein Dlxin-1 and regulates its intracellular distribution. |journal=J. Biol. Chem. |volume=278 |issue= 31 |pages= 29057–64 |year= 2003 |pmid= 12754255 |doi= 10.1074/jbc.M302199200
*cite journal | author=Wen CJ, Xue B, Qin WX, "et al." |title=hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation. |journal=FEBS Lett. |volume=564 |issue= 1-2 |pages= 171–6 |year= 2004 |pmid= 15094062 |doi= 10.1016/S0014-5793(04)00353-9
*cite journal | author=Bertrand M, Huijbers I, Chomez P, De Backer O |title=Comparative expression analysis of the MAGED genes during embryogenesis and brain development. |journal=Dev. Dyn. |volume=230 |issue= 2 |pages= 325–34 |year= 2005 |pmid= 15162511 |doi= 10.1002/dvdy.20026
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ross MT, Grafham DV, Coffey AJ, "et al." |title=The DNA sequence of the human X chromosome. |journal=Nature |volume=434 |issue= 7031 |pages= 325–37 |year= 2005 |pmid= 15772651 |doi= 10.1038/nature03440
*cite journal | author=Tian XX, Rai D, Li J, "et al." |title=BRCA2 suppresses cell proliferation via stabilizing MAGE-D1. |journal=Cancer Res. |volume=65 |issue= 11 |pages= 4747–53 |year= 2005 |pmid= 15930293 |doi= 10.1158/0008-5472.CAN-05-0018
*cite journal | author=Xue B, Wen C, Shi Y, "et al." |title=Human NRAGE disrupts E-cadherin/beta-catenin regulated homotypic cell-cell adhesion. |journal=Biochem. Biophys. Res. Commun. |volume=336 |issue= 1 |pages= 247–51 |year= 2005 |pmid= 16125672 |doi= 10.1016/j.bbrc.2005.08.069
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032

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