EGLN1


EGLN1

Egl nine homolog 1 (C. elegans), also known as EGLN1, is a human gene.cite web | title = Entrez Gene: EGLN1 egl nine homolog 1 (C. elegans)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54583| accessdate = ]

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References

Further reading

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*cite journal | author=Semenza GL |title=HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. |journal=Cell |volume=107 |issue= 1 |pages= 1–3 |year= 2001 |pmid= 11595178 |doi=10.1016/S0092-8674(01)00518-9
*cite journal | author=Wax SD, Tsao L, Lieb ME, "et al." |title=SM-20 is a novel 40-kd protein whose expression in the arterial wall is restricted to smooth muscle. |journal=Lab. Invest. |volume=74 |issue= 4 |pages= 797–808 |year= 1996 |pmid= 8606489 |doi=
*cite journal | author=Dupuy D, Aubert I, Dupérat VG, "et al." |title=Mapping, characterization, and expression analysis of the SM-20 human homologue, c1orf12, and identification of a novel related gene, SCAND2. |journal=Genomics |volume=69 |issue= 3 |pages= 348–54 |year= 2001 |pmid= 11056053 |doi= 10.1006/geno.2000.6343
*cite journal | author=Taylor MS |title=Characterization and comparative analysis of the EGLN gene family. |journal=Gene |volume=275 |issue= 1 |pages= 125–32 |year= 2001 |pmid= 11574160 |doi=10.1016/S0378-1119(01)00633-3
*cite journal | author=Epstein AC, Gleadle JM, McNeill LA, "et al." |title=C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. |journal=Cell |volume=107 |issue= 1 |pages= 43–54 |year= 2001 |pmid= 11595184 |doi=10.1016/S0092-8674(01)00507-4
*cite journal | author=Oehme F, Ellinghaus P, Kolkhof P, "et al." |title=Overexpression of PH-4, a novel putative proline 4-hydroxylase, modulates activity of hypoxia-inducible transcription factors. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 2 |pages= 343–9 |year= 2002 |pmid= 12163023 |doi=10.1016/S0006-291X(02)00862-8
*cite journal | author=Ivan M, Haberberger T, Gervasi DC, "et al." |title=Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 21 |pages= 13459–64 |year= 2002 |pmid= 12351678 |doi= 10.1073/pnas.192342099
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Metzen E, Berchner-Pfannschmidt U, Stengel P, "et al." |title=Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing. |journal=J. Cell. Sci. |volume=116 |issue= Pt 7 |pages= 1319–26 |year= 2003 |pmid= 12615973 |doi=10.1242/jcs.00318
*cite journal | author=Cioffi CL, Liu XQ, Kosinski PA, "et al." |title=Differential regulation of HIF-1 alpha prolyl-4-hydroxylase genes by hypoxia in human cardiovascular cells. |journal=Biochem. Biophys. Res. Commun. |volume=303 |issue= 3 |pages= 947–53 |year= 2003 |pmid= 12670503 |doi=10.1016/S0006-291X(03)00453-4
*cite journal | author=Berra E, Benizri E, Ginouvès A, "et al." |title=HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia. |journal=Embo J. |volume=22 |issue= 16 |pages= 4082–90 |year= 2003 |pmid= 12912907 |doi= 10.1093/emboj/cdg392
*cite journal | author=Aprelikova O, Chandramouli GV, Wood M, "et al." |title=Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors. |journal=J. Cell. Biochem. |volume=92 |issue= 3 |pages= 491–501 |year= 2004 |pmid= 15156561 |doi= 10.1002/jcb.20067
*cite journal | author=Appelhoff RJ, Tian YM, Raval RR, "et al." |title=Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. |journal=J. Biol. Chem. |volume=279 |issue= 37 |pages= 38458–65 |year= 2004 |pmid= 15247232 |doi= 10.1074/jbc.M406026200
*cite journal | author=Metzen E, Stiehl DP, Doege K, "et al." |title=Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element. |journal=Biochem. J. |volume=387 |issue= Pt 3 |pages= 711–7 |year= 2006 |pmid= 15563275 |doi= 10.1042/BJ20041736
*cite journal | author=Baek JH, Mahon PC, Oh J, "et al." |title=OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha. |journal=Mol. Cell |volume=17 |issue= 4 |pages= 503–12 |year= 2005 |pmid= 15721254 |doi= 10.1016/j.molcel.2005.01.011
*cite journal | author=Ozer A, Wu LC, Bruick RK |title=The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF). |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=102 |issue= 21 |pages= 7481–6 |year= 2005 |pmid= 15897452 |doi= 10.1073/pnas.0502716102
*cite journal | author=Choi KO, Lee T, Lee N, "et al." |title=Inhibition of the catalytic activity of hypoxia-inducible factor-1alpha-prolyl-hydroxylase 2 by a MYND-type zinc finger. |journal=Mol. Pharmacol. |volume=68 |issue= 6 |pages= 1803–9 |year= 2006 |pmid= 16155211 |doi= 10.1124/mol.105.015271
*cite journal | author=To KK, Huang LE |title=Suppression of hypoxia-inducible factor 1alpha (HIF-1alpha) transcriptional activity by the HIF prolyl hydroxylase EGLN1. |journal=J. Biol. Chem. |volume=280 |issue= 45 |pages= 38102–7 |year= 2006 |pmid= 16157596 |doi= 10.1074/jbc.M504342200
*cite journal | author=Kato H, Inoue T, Asanoma K, "et al." |title=Induction of human endometrial cancer cell senescence through modulation of HIF-1alpha activity by EGLN1. |journal=Int. J. Cancer |volume=118 |issue= 5 |pages= 1144–53 |year= 2006 |pmid= 16161047 |doi= 10.1002/ijc.21488

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