PIK3CB


PIK3CB
Phosphoinositide-3-kinase, catalytic, beta polypeptide
Identifiers
Symbols PIK3CB; DKFZp779K1237; MGC133043; P110BETA; PI3K; PI3KBETA; PIK3C1
External IDs OMIM602925 MGI1922019 HomoloGene21250 GeneCards: PIK3CB Gene
EC number 2.7.1.153
RNA expression pattern
PBB GE PIK3CB 212688 at tn.png
PBB GE PIK3CB 217620 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5291 74769
Ensembl ENSG00000051382 ENSMUSG00000032462
UniProt P42338 Q8BTI9
RefSeq (mRNA) NM_006219 NM_029094.3
RefSeq (protein) NP_006210 NP_083370.2
Location (UCSC) Chr 3:
138.37 – 138.55 Mb
Chr 9:
98.94 – 99.04 Mb
PubMed search [1] [2]

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene.[1][2]

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993).[supplied by OMIM][2]

References

Further reading


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