CEACAM6

CEACAM6

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) also known as CD66c (Cluster of Differentiation 66c), is a human gene.cite web | title = Entrez Gene: CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4680| accessdate = ]

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ee also

* Cluster of differentiation

References

Further reading

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*cite journal | author=Oikawa S, Inuzuka C, Kuroki M, "et al." |title=A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains. |journal=J. Biol. Chem. |volume=266 |issue= 13 |pages= 7995–8001 |year= 1991 |pmid= 2022629 |doi=
*cite journal | author=Haus O, Noworolska A, Laskowski M, "et al." |title=Prognostic significance of secondary cytogenetic changes and nonspecific cross-reacting antigen (NCA) in patients with Ph-positive chronic myeloid leukemia. |journal=Exp. Mol. Pathol. |volume=52 |issue= 2 |pages= 235–42 |year= 1990 |pmid= 2332039 |doi=
*cite journal | author=Hefta SA, Paxton RJ, Shively JE |title=Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometry. |journal=J. Biol. Chem. |volume=265 |issue= 15 |pages= 8618–26 |year= 1990 |pmid= 2341397 |doi=
*cite journal | author=Inazawa J, Abe T, Inoue K, "et al." |title=Regional assignment of nonspecific cross-reacting antigen (NCA) of the CEA gene family to chromosome 19 at band q13.2. |journal=Cytogenet. Cell Genet. |volume=52 |issue= 1-2 |pages= 28–31 |year= 1990 |pmid= 2612212 |doi=
*cite journal | author=Neumaier M, Zimmermann W, Shively L, "et al." |title=Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. |journal=J. Biol. Chem. |volume=263 |issue= 7 |pages= 3202–7 |year= 1988 |pmid= 2830274 |doi=
*cite journal | author=Kuroki M, Kuroki M, Moore GE, "et al." |title=The molecular heterogeneity of nonspecific cross-reacting antigen synthesized by tumor cells and granulocytes. |journal=Jpn. J. Cancer Res. |volume=79 |issue= 1 |pages= 82–90 |year= 1988 |pmid= 3128509 |doi=
*cite journal | author=Barnett T, Goebel SJ, Nothdurft MA, Elting JJ |title=Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. |journal=Genomics |volume=3 |issue= 1 |pages= 59–66 |year= 1989 |pmid= 3220478 |doi=
*cite journal | author=Tawaragi Y, Oikawa S, Matsuoka Y, "et al." |title=Primary structure of nonspecific crossreacting antigen (NCA), a member of carcinoembryonic antigen (CEA) gene family, deduced from cDNA sequence. |journal=Biochem. Biophys. Res. Commun. |volume=150 |issue= 1 |pages= 89–96 |year= 1988 |pmid= 3337731 |doi=
*cite journal | author=Noworolska A, Harłozińska-Szmyrka A, Richter R |title=Distribution of surface nonspecific cross-reacting antigen and influence of proteolytic enzymes on this antigen in myeloid cell series. |journal=Cancer Detect. Prev. |volume=9 |issue= 3-4 |pages= 365–71 |year= 1986 |pmid= 3527416 |doi=
*cite journal | author=Oikawa S, Kosaki G, Nakazato H |title=Molecular cloning of a gene for a member of carcinoembryonic antigen (CEA) gene family; signal peptide and N-terminal domain sequences of nonspecific crossreacting antigen (NCA). |journal=Biochem. Biophys. Res. Commun. |volume=146 |issue= 2 |pages= 464–9 |year= 1987 |pmid= 3619891 |doi=
*cite journal | author=Watt SM, Fawcett J, Murdoch SJ, "et al." |title=CD66 identifies the biliary glycoprotein (BGP) adhesion molecule: cloning, expression, and adhesion functions of the BGPc splice variant. |journal=Blood |volume=84 |issue= 1 |pages= 200–10 |year= 1994 |pmid= 8018919 |doi=
*cite journal | author=Honda Y, Egawa K, Kuroki M, Ono T |title=Hair cycle-dependent expression of a nonspecific cross reacting antigen (NCA)-50/90-like molecule on follicular keratinocytes. |journal=Arch. Dermatol. Res. |volume=289 |issue= 8 |pages= 457–65 |year= 1997 |pmid= 9266023 |doi=
*cite journal | author=Schölzel S, Zimmermann W, Schwarzkopf G, "et al." |title=Carcinoembryonic antigen family members CEACAM6 and CEACAM7 are differentially expressed in normal tissues and oppositely deregulated in hyperplastic colorectal polyps and early adenomas. |journal=Am. J. Pathol. |volume=156 |issue= 2 |pages= 595–605 |year= 2000 |pmid= 10666389 |doi=
*cite journal | author=Oikawa S, Sugiyama M, Kuroki M, "et al." |title=Extracellular N-domain alone can mediate specific heterophilic adhesion between members of the carcinoembryonic antigen family, CEACAM6 and CEACAM8. |journal=Biochem. Biophys. Res. Commun. |volume=278 |issue= 3 |pages= 564–8 |year= 2001 |pmid= 11095950 |doi= 10.1006/bbrc.2000.3858
*cite journal | author=Ilantzis C, DeMarte L, Screaton RA, Stanners CP |title=Deregulated expression of the human tumor marker CEA and CEA family member CEACAM6 disrupts tissue architecture and blocks colonocyte differentiation. |journal=Neoplasia |volume=4 |issue= 2 |pages= 151–63 |year= 2002 |pmid= 11896570 |doi= 10.1038/sj/neo/7900201
*cite journal | author=Singer BB, Scheffrahn I, Heymann R, "et al." |title=Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes. |journal=J. Immunol. |volume=168 |issue= 10 |pages= 5139–46 |year= 2002 |pmid= 11994468 |doi=
*cite journal | author=Skubitz KM, Campbell KD, Skubitz AP |title=Synthetic peptides from the N-domains of CEACAMs activate neutrophils. |journal=J. Pept. Res. |volume=58 |issue= 6 |pages= 515–26 |year= 2002 |pmid= 12005421 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Taheri M, Saragovi HU, Stanners CP |title=The adhesion and differentiation-inhibitory activities of the immunoglobulin superfamily member, carcinoembryonic antigen, can be independently blocked. |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 14632–9 |year= 2003 |pmid= 12571231 |doi= 10.1074/jbc.M212500200
*cite journal | author=Duxbury MS, Ito H, Zinner MJ, "et al." |title=CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. |journal=Oncogene |volume=23 |issue= 2 |pages= 465–73 |year= 2004 |pmid= 14724575 |doi= 10.1038/sj.onc.1207036

External links

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  • Carcinoembryonic antigen — (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in… …   Wikipedia

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  • CEACAM7 — Carcinoembryonic antigen related cell adhesion molecule 7, also known as CEACAM7, is a human gene.cite web | title = Entrez Gene: CEACAM7 carcinoembryonic antigen related cell adhesion molecule 7| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db …   Wikipedia

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