Upstream transcription factor 2, c-fos interacting, also known as USF2, is a human gene.cite web | title = Entrez Gene: USF2 upstream transcription factor 2, c-fos interacting| url =| accessdate = ]

section_title =
summary_text = This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.cite web | title = Entrez Gene: USF2 upstream transcription factor 2, c-fos interacting| url =| accessdate = ]


Further reading

citations =
*cite journal | author=Corre S, Galibert MD |title= [USF as a key regulatory element of gene expression] |journal=Med Sci (Paris) |volume=22 |issue= 1 |pages= 62–7 |year= 2006 |pmid= 16386222 |doi=
*cite journal | author=Sirito M, Walker S, Lin Q, "et al." |title=Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers. |journal=Gene Expr. |volume=2 |issue= 3 |pages= 231–40 |year= 1993 |pmid= 1450663 |doi=
*cite journal | author=Blanar MA, Rutter WJ |title=Interaction cloning: identification of a helix-loop-helix zipper protein that interacts with c-Fos. |journal=Science |volume=256 |issue= 5059 |pages= 1014–8 |year= 1992 |pmid= 1589769 |doi=
*cite journal | author=Viollet B, Lefrançois-Martinez AM, Henrion A, "et al." |title=Immunochemical characterization and transacting properties of upstream stimulatory factor isoforms. |journal=J. Biol. Chem. |volume=271 |issue= 3 |pages= 1405–15 |year= 1996 |pmid= 8576131 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Groenen PM, Garcia E, Debeer P, "et al." |title=Structure, sequence, and chromosome 19 localization of human USF2 and its rearrangement in a patient with multicystic renal dysplasia. |journal=Genomics |volume=38 |issue= 2 |pages= 141–8 |year= 1997 |pmid= 8954795 |doi=
*cite journal | author=Ghosh AK, Datta PK, Jacob ST |title=The dual role of helix-loop--helix-zipper protein USF in ribosomal RNA gene transcription in vivo. |journal=Oncogene |volume=14 |issue= 5 |pages= 589–94 |year= 1997 |pmid= 9053857 |doi= 10.1038/sj.onc.1200866
*cite journal | author=Kurschner C, Morgan JI |title=USF2/FIP associates with the b-Zip transcription factor, c-Maf, via its bHLH domain and inhibits c-Maf DNA binding activity. |journal=Biochem. Biophys. Res. Commun. |volume=231 |issue= 2 |pages= 333–9 |year= 1997 |pmid= 9070273 |doi= 10.1006/bbrc.1997.6097
*cite journal | author=Breen GA, Jordan EM |title=Regulation of the nuclear gene that encodes the alpha-subunit of the mitochondrial F0F1-ATP synthase complex. Activation by upstream stimulatory factor 2. |journal=J. Biol. Chem. |volume=272 |issue= 16 |pages= 10538–42 |year= 1997 |pmid= 9099698 |doi=
*cite journal | author=Nechushtan H, Zhang Z, Razin E |title=Microphthalmia (mi) in murine mast cells: regulation of its stimuli-mediated expression on the translational level. |journal=Blood |volume=89 |issue= 8 |pages= 2999–3008 |year= 1997 |pmid= 9108421 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Breen GA, Jordan EM |title=Transcriptional activation of the F(1)F(0) ATP synthase alpha-subunit initiator element by USF2 is mediated by p300. |journal=Biochim. Biophys. Acta |volume=1428 |issue= 2-3 |pages= 169–76 |year= 1999 |pmid= 10434034 |doi=
*cite journal | author=Kumari D, Usdin K |title=Interaction of the transcription factors USF1, USF2, and alpha -Pal/Nrf-1 with the FMR1 promoter. Implications for Fragile X mental retardation syndrome. |journal=J. Biol. Chem. |volume=276 |issue= 6 |pages= 4357–64 |year= 2001 |pmid= 11058604 |doi= 10.1074/jbc.M009629200
*cite journal | author=Kolonics A, Apáti A, Nahajevszky S, "et al." |title=Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia. |journal=Haematologia (Budap) |volume=31 |issue= 2 |pages= 125–38 |year= 2002 |pmid= 11583024 |doi=
*cite journal | author=Bengtsson SH, Madeyski-Bengtson K, Nilsson J, Bjursell G |title=Transcriptional regulation of the human carboxyl ester lipase gene in THP-1 monocytes: an E-box required for activation binds upstream stimulatory factors 1 and 2. |journal=Biochem. J. |volume=365 |issue= Pt 2 |pages= 481–8 |year= 2002 |pmid= 11945176 |doi= 10.1042/BJ20020223
*cite journal | author=Villavicencio EH, Yoon JW, Frank DJ, "et al." |title=Cooperative E-box regulation of human GLI1 by TWIST and USF. |journal=Genesis |volume=32 |issue= 4 |pages= 247–58 |year= 2002 |pmid= 11948912 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Moore ML, Park EA, McMillin JB |title=Upstream stimulatory factor represses the induction of carnitine palmitoyltransferase-Ibeta expression by PGC-1. |journal=J. Biol. Chem. |volume=278 |issue= 19 |pages= 17263–8 |year= 2003 |pmid= 12611894 |doi= 10.1074/jbc.M210486200
*cite journal | author=Pickwell GV, Shih H, Quattrochi LC |title=Interaction of upstream stimulatory factor proteins with an E-box located within the human CYP1A2 5'-flanking gene contributes to basal transcriptional gene activation. |journal=Biochem. Pharmacol. |volume=65 |issue= 7 |pages= 1087–96 |year= 2003 |pmid= 12663044 |doi=
*cite journal | author=Zhu J, Giannola DM, Zhang Y, "et al." |title=NF-Y cooperates with USF1/2 to induce the hematopoietic expression of HOXB4. |journal=Blood |volume=102 |issue= 7 |pages= 2420–7 |year= 2003 |pmid= 12791656 |doi= 10.1182/blood-2003-01-0251

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