ERCC6

ERCC6

Excision repair cross-complementing rodent repair deficiency, complementation group 6, also known as ERCC6, is a human gene.cite web | title = Entrez Gene: ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2074| accessdate = ]

PBB_Summary
section_title =
summary_text = The ERCC6 protein is a DNA-binding protein important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites.cite web | title = Entrez Gene: ERCC6 excision repair cross-complementing rodent repair deficiency, complementation group 6| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2074| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Cleaver JE, Thompson LH, Richardson AS, States JC |title=A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy. |journal=Hum. Mutat. |volume=14 |issue= 1 |pages= 9–22 |year= 1999 |pmid= 10447254 |doi= 10.1002/(SICI)1098-1004(1999)14:1<9::AID-HUMU2>3.0.CO;2-6 |doilabel=10.1002/(SICI)1098-1004(1999)14:19::AID-HUMU23.0.CO;2-6
*cite journal | author=Troelstra C, van Gool A, de Wit J, "et al." |title=ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes. |journal=Cell |volume=71 |issue= 6 |pages= 939–53 |year= 1993 |pmid= 1339317 |doi=
*cite journal | author=Troelstra C, Landsvater RM, Wiegant J, "et al." |title=Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21. |journal=Genomics |volume=12 |issue= 4 |pages= 745–9 |year= 1992 |pmid= 1349298 |doi=
*cite journal | author=Fryns JP, Bulcke J, Verdu P, "et al." |title=Apparent late-onset Cockayne syndrome and interstitial deletion of the long arm of chromosome 10 (del(10)(q11.23q21.2)). |journal=Am. J. Med. Genet. |volume=40 |issue= 3 |pages= 343–4 |year= 1991 |pmid= 1951442 |doi= 10.1002/ajmg.1320400320
*cite journal | author=Troelstra C, Odijk H, de Wit J, "et al." |title=Molecular cloning of the human DNA excision repair gene ERCC-6. |journal=Mol. Cell. Biol. |volume=10 |issue= 11 |pages= 5806–13 |year= 1990 |pmid= 2172786 |doi=
*cite journal | author=Wang XW, Yeh H, Schaeffer L, "et al." |title=p53 modulation of TFIIH-associated nucleotide excision repair activity. |journal=Nat. Genet. |volume=10 |issue= 2 |pages= 188–95 |year= 1995 |pmid= 7663514 |doi= 10.1038/ng0695-188
*cite journal | author=Henning KA, Li L, Iyer N, "et al." |title=The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. |journal=Cell |volume=82 |issue= 4 |pages= 555–64 |year= 1995 |pmid= 7664335 |doi=
*cite journal | author=Troelstra C, Hesen W, Bootsma D, Hoeijmakers JH |title=Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B. |journal=Nucleic Acids Res. |volume=21 |issue= 3 |pages= 419–26 |year= 1993 |pmid= 8382798 |doi=
*cite journal | author=Iyer N, Reagan MS, Wu KJ, "et al." |title=Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein. |journal=Biochemistry |volume=35 |issue= 7 |pages= 2157–67 |year= 1996 |pmid= 8652557 |doi= 10.1021/bi9524124
*cite journal | author=Selby CP, Sancar A |title=Human transcription-repair coupling factor CSB/ERCC6 is a DNA-stimulated ATPase but is not a helicase and does not disrupt the ternary transcription complex of stalled RNA polymerase II. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1885–90 |year= 1997 |pmid= 8999876 |doi=
*cite journal | author=Boulikas T |title=Nuclear import of DNA repair proteins. |journal=Anticancer Res. |volume=17 |issue= 2A |pages= 843–63 |year= 1997 |pmid= 9137418 |doi=
*cite journal | author=Selby CP, Sancar A |title=Cockayne syndrome group B protein enhances elongation by RNA polymerase II. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11205–9 |year= 1997 |pmid= 9326587 |doi=
*cite journal | author=Tantin D, Kansal A, Carey M |title=Recruitment of the putative transcription-repair coupling factor CSB/ERCC6 to RNA polymerase II elongation complexes. |journal=Mol. Cell. Biol. |volume=17 |issue= 12 |pages= 6803–14 |year= 1997 |pmid= 9372911 |doi=
*cite journal | author=Mallery DL, Tanganelli B, Colella S, "et al." |title=Molecular analysis of mutations in the CSB (ERCC6) gene in patients with Cockayne syndrome. |journal=Am. J. Hum. Genet. |volume=62 |issue= 1 |pages= 77–85 |year= 1998 |pmid= 9443879 |doi=
*cite journal | author=Lindsay HD, Griffiths DJ, Edwards RJ, "et al." |title=S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. |journal=Genes Dev. |volume=12 |issue= 3 |pages= 382–95 |year= 1998 |pmid= 9450932 |doi=
*cite journal | author=Tantin D |title=RNA polymerase II elongation complexes containing the Cockayne syndrome group B protein interact with a molecular complex containing the transcription factor IIH components xeroderma pigmentosum B and p62. |journal=J. Biol. Chem. |volume=273 |issue= 43 |pages= 27794–9 |year= 1998 |pmid= 9774388 |doi=
*cite journal | author=Dianov G, Bischoff C, Sunesen M, Bohr VA |title=Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells. |journal=Nucleic Acids Res. |volume=27 |issue= 5 |pages= 1365–8 |year= 1999 |pmid= 9973627 |doi=
*cite journal | author=Colella S, Nardo T, Mallery D, "et al." |title=Alterations in the CSB gene in three Italian patients with the severe form of Cockayne syndrome (CS) but without clinical photosensitivity. |journal=Hum. Mol. Genet. |volume=8 |issue= 5 |pages= 935–41 |year= 1999 |pmid= 10196384 |doi=
*cite journal | author=Cheng L, Guan Y, Li L, "et al." |title=Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=8 |issue= 9 |pages= 801–7 |year= 1999 |pmid= 10498399 |doi=

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем решить контрольную работу

Look at other dictionaries:

  • Cockayne syndrome — Classification and external resources ICD 10 Q87.1 (ILDS Q87.110) ICD 9 759.8 …   Wikipedia

  • Síndrome de Cockayne — Clasificación y recursos externos CIE 10 Q87.1 CIE 9 759.8 DiseasesDB …   Wikipedia Español

  • Helicase — Structure of E. coli helicase RuvA Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands (i.e.,… …   Wikipedia

  • DNA repair — For the journal, see DNA Repair (journal). DNA damage resulting in multiple broken chromosomes DNA repair refers to a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. In human… …   Wikipedia

  • Xeroderma pigmentosum — XP1 redirects here. For the phone, see Sonim XP1 ToughPhone. Xeroderma pigmentosum Classification and external resources ICD 10 Q82.1 ICD 9 …   Wikipedia

  • Non-homologous end joining — (NHEJ) is a pathway that repairs double strand breaks in DNA. NHEJ is referred to as non homologous because the break ends are directly ligated without the need for a homologous template, in contrast to homologous recombination, which requires a… …   Wikipedia

  • Nucleotide excision repair — Diagram[1] Nucleotide excision repair is a DNA repair mechanism.[2] DNA constantly requires r …   Wikipedia

  • DNA mismatch repair — is a system for recognizing and repairing erroneous insertion, deletion and mis incorporation of bases that can arise during DNA replication and recombination, as well as repairing some forms of DNA damage.[1][2] Mismatch repair is strand… …   Wikipedia

  • Chromosome 10 (human) — Chromosome 10 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 10 spans about 135 million base pairs (the building material of DNA) and represents between 4 and 4.5 percent of the… …   Wikipedia

  • MSH2 — MutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) PDB rendering based on 2o8b …   Wikipedia

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”