Defensin, beta 1

Defensin, beta 1
Defensin, beta 1

PDB rendering based on 1e4s.
Identifiers
Symbols DEFB1; BD1; DEFB-1; DEFB101; HBD1; MGC51822
External IDs OMIM602056 HomoloGene88476 GeneCards: DEFB1 Gene
RNA expression pattern
PBB GE DEFB1 210397 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1672 n/a
Ensembl ENSG00000164825 n/a
UniProt P60022 n/a
RefSeq (mRNA) NM_005218 n/a
RefSeq (protein) NP_005209 n/a
Location (UCSC) Chr 8:
6.73 – 6.74 Mb
n/a
PubMed search [1] n/a

Beta-defensin 1 is a protein that in humans is encoded by the DEFB1 gene.[1][2]

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member defensin, alpha 1, and has been implicated in the pathogenesis of cystic fibrosis.[2]

References

  1. ^ Bensch KW, Raida M, Magert HJ, Schulz-Knappe P, Forssmann WG (Sep 1995). "hBD-1: a novel beta-defensin from human plasma". FEBS Lett 368 (2): 331–5. doi:10.1016/0014-5793(95)00687-5. PMID 7628632. 
  2. ^ a b "Entrez Gene: DEFB1 defensin, beta 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1672. 

Further reading


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать курсовую

Look at other dictionaries:

  • Beta-defensin 2 — Defensin, beta 4A PDB rendering based on 1e4q …   Wikipedia

  • Defensin — Monomeric and dimeric structures of human beta defensin HBD 2 Defensins are small cysteine rich cationic proteins found in both vertebrates and invertebrates. They have also been reported in plants.[1] …   Wikipedia

  • Beta defensin — Pfam box Symbol = Defensin beta Name = Beta defensin width =200 caption = Pfam= PF00711 InterPro= IPR001855 SMART= Prosite = SCOP = 1bnb TCDB = OPM family= 56 OPM protein= 1ut3 PDB=PDB3|1ijuC:33 68 PDB3|1kj5A:33 68 PDB3|1ijvB:33 68PDB3|1e4sA:33… …   Wikipedia

  • Alpha defensin — Mammalian defensin Structure of defensin HNP 3.[1] Identifiers Symbol Defensin 1 …   Wikipedia

  • DEFB103A — Defensin, beta 103B PDB rendering based on 1kj6 …   Wikipedia

  • DEFB4 — Defensin, beta 4, also known as DEFB4, is a human gene. PBB Summary section title = summary text = Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein… …   Wikipedia

  • DEFB104A — Defensin, beta 104A Identifiers Symbols DEFB104A; BD 4; DEFB 4; DEFB104; DEFB104B; DEFB4; MGC118942; MGC118944; MGC118945; hBD 4 External IDs …   Wikipedia

  • DEFB106A — Defensin, beta 106A Identifiers Symbols DEFB106A; BD 6; DEFB 6; DEFB106; MGC118938; MGC118939; MGC118940; MGC118941; MGC133011; MGC133012 External IDs …   Wikipedia

  • DEFB105A — Defensin, beta 105A Identifiers Symbols DEFB105A; BD 5; DEFB 5; DEFB105; DEFB105B External IDs …   Wikipedia

  • DEFB129 — Defensin, beta 129 Identifiers Symbols DEFB129; C20orf87; DEFB 29; DEFB29; bA530N10.3; hBD 29 External IDs …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”