FGF7


FGF7

Fibroblast growth factor 7 (keratinocyte growth factor), also known as FGF7, is a human gene.cite web | title = Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2252| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.cite web | title = Entrez Gene: FGF7 fibroblast growth factor 7 (keratinocyte growth factor)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2252| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Beer HD, Gassmann MG, Munz B, "et al." |title=Expression and function of keratinocyte growth factor and activin in skin morphogenesis and cutaneous wound repair. |journal=J. Investig. Dermatol. Symp. Proc. |volume=5 |issue= 1 |pages= 34–9 |year= 2001 |pmid= 11147673 |doi= 10.1046/j.1087-0024.2000.00009.x
*cite journal | author=Ware LB, Matthay MA |title=Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair. |journal=Am. J. Physiol. Lung Cell Mol. Physiol. |volume=282 |issue= 5 |pages= L924–40 |year= 2002 |pmid= 11943656 |doi= 10.1152/ajplung.00439.2001
*cite journal | author=Finch PW, Rubin JS |title=Keratinocyte growth factor/fibroblast growth factor 7, a homeostatic factor with therapeutic potential for epithelial protection and repair. |journal=Adv. Cancer Res. |volume=91 |issue= |pages= 69–136 |year= 2004 |pmid= 15327889 |doi= 10.1016/S0065-230X(04)91003-2
*cite journal | author=Ishibashi T, Bottaro DP, Chan A, "et al." |title=Expression cloning of a human dual-specificity phosphatase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 24 |pages= 12170–4 |year= 1993 |pmid= 1281549 |doi=
*cite journal | author=Kelley MJ, Pech M, Seuanez HN, "et al." |title=Emergence of the keratinocyte growth factor multigene family during the great ape radiation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 19 |pages= 9287–91 |year= 1992 |pmid= 1409637 |doi=
*cite journal | author=Aaronson SA, Bottaro DP, Miki T, "et al." |title=Keratinocyte growth factor. A fibroblast growth factor family member with unusual target cell specificity. |journal=Ann. N. Y. Acad. Sci. |volume=638 |issue= |pages= 62–77 |year= 1992 |pmid= 1664700 |doi=
*cite journal | author=Finch PW, Rubin JS, Miki T, "et al." |title=Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. |journal=Science |volume=245 |issue= 4919 |pages= 752–5 |year= 1989 |pmid= 2475908 |doi=
*cite journal | author=Rubin JS, Osada H, Finch PW, "et al." |title=Purification and characterization of a newly identified growth factor specific for epithelial cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 3 |pages= 802–6 |year= 1989 |pmid= 2915979 |doi=
*cite journal | author=Ron D, Reich R, Chedid M, "et al." |title=Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. |journal=J. Biol. Chem. |volume=268 |issue= 8 |pages= 5388–94 |year= 1993 |pmid= 7680645 |doi=
*cite journal | author=Yan G, Fukabori Y, McBride G, "et al." |title=Exon switching and activation of stromal and embryonic fibroblast growth factor (FGF)-FGF receptor genes in prostate epithelial cells accompany stromal independence and malignancy. |journal=Mol. Cell. Biol. |volume=13 |issue= 8 |pages= 4513–22 |year= 1993 |pmid= 7687739 |doi=
*cite journal | author=Mattei MG, deLapeyrière O, Bresnick J, "et al." |title=Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively. |journal=Mamm. Genome |volume=6 |issue= 3 |pages= 196–7 |year= 1995 |pmid= 7749227 |doi=
*cite journal | author=Werner S, Smola H, Liao X, "et al." |title=The function of KGF in morphogenesis of epithelium and reepithelialization of wounds. |journal=Science |volume=266 |issue= 5186 |pages= 819–22 |year= 1994 |pmid= 7973639 |doi=
*cite journal | author=Wilson SE, Walker JW, Chwang EL, He YG |title=Hepatocyte growth factor, keratinocyte growth factor, their receptors, fibroblast growth factor receptor-2, and the cells of the cornea. |journal=Invest. Ophthalmol. Vis. Sci. |volume=34 |issue= 8 |pages= 2544–61 |year= 1993 |pmid= 8392040 |doi=
*cite journal | author=Guo L, Degenstein L, Fuchs E |title=Keratinocyte growth factor is required for hair development but not for wound healing. |journal=Genes Dev. |volume=10 |issue= 2 |pages= 165–75 |year= 1996 |pmid= 8566750 |doi=
*cite journal | author=Ornitz DM, Xu J, Colvin JS, "et al." |title=Receptor specificity of the fibroblast growth factor family. |journal=J. Biol. Chem. |volume=271 |issue= 25 |pages= 15292–7 |year= 1996 |pmid= 8663044 |doi=
*cite journal | author=Post M, Souza P, Liu J, "et al." |title=Keratinocyte growth factor and its receptor are involved in regulating early lung branching. |journal=Development |volume=122 |issue= 10 |pages= 3107–15 |year= 1996 |pmid= 8898224 |doi=
*cite journal | author=Zimonjic DB, Kelley MJ, Rubin JS, "et al." |title=Fluorescence in situ hybridization analysis of keratinocyte growth factor gene amplification and dispersion in evolution of great apes and humans. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 21 |pages= 11461–5 |year= 1997 |pmid= 9326632 |doi=
*cite journal | author=Winkles JA, Alberts GF, Chedid M, "et al." |title=Differential expression of the keratinocyte growth factor (KGF) and KGF receptor genes in human vascular smooth muscle cells and arteries. |journal=J. Cell. Physiol. |volume=173 |issue= 3 |pages= 380–6 |year= 1997 |pmid= 9369951 |doi= 10.1002/(SICI)1097-4652(199712)173:3<380::AID-JCP10>3.0.CO;2-G |doilabel=10.1002/(SICI)1097-4652(199712)173:3380::AID-JCP103.0.CO;2-G
*cite journal | author=Ishibashi T, Tanaka T, Nibu K, "et al." |title=Keratinocyte growth factor and its receptor messenger RNA expression in nasal mucosa and nasal polyps. |journal=Ann. Otol. Rhinol. Laryngol. |volume=107 |issue= 10 Pt 1 |pages= 885–90 |year= 1998 |pmid= 9794620 |doi=
*cite journal | author=Mongiat M, Taylor K, Otto J, "et al." |title=The protein core of the proteoglycan perlecan binds specifically to fibroblast growth factor-7. |journal=J. Biol. Chem. |volume=275 |issue= 10 |pages= 7095–100 |year= 2000 |pmid= 10702276 |doi=

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