N-arachidonoyl-dopamine

N-arachidonoyl-dopamine

Chembox new
ImageFile = NADA.png ImageSize = 275px
IUPACName = (5Z,8Z,11Z,14Z)-N- [2-(3,4-dihydroxyphenyl)ethyl] icosa-5,8,11,14-tetraenamide
OtherNames = NADA
Section1 = Chembox Identifiers
CASNo = 199875-69-9
PubChem = 5282105
SMILES = CCCCCC=C/CC=C/CC=C/CC=C/CCCC(=O)NCCC1=CC(=C(C=C1)O)O
MeSHName =

Section2 = Chembox Properties
Formula = C28H41NO3
MolarMass = 439.63 g/mol
Appearance =
Density =
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Section3 = Chembox Hazards
Solubility =
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N-arachidonoyl-dopamine, or NADA is a ligand (or chemical 'key') agonist (activator) to CB1 receptors which is an activation site for endocannabinoid and endovanilloid (aka vanilloid) ligandscite journal
journal =European journal of pharmacology
year=2003
month=July
volume=472
issue=1-2
pages=1–21
title=Cannabinoid modulation of peripheral autonomic and sensory neurotransmission.
author=Ralevic V.
pmid=12860468
doi=10.1016/S0014-2999(03)01813-2
] . Specifically, NADA binds to both TRPV1 (a TRP-vanilloid cation channel receptor) and CB1 (an endocannabinoid receptor), a peculiarity among neurochemicals which normally bind to only one type of receptor.

References

External links

* [http://www.caymanchem.com/app/template/Product.vm/catalog/90057/tab/data/a/z General information] about NADA.


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