- Bromethalin
Chembox new
ImageFile=Bromethalin.png
ImageSize=200px
IUPACName="N"-Methyl-2,4-dinitro-"N"-(2,4,6-tribromophenyl)-6-(trifluoromethyl)aniline
OtherNames=
Section1= Chembox Identifiers
CASNo=63333-35-7
PubChem=44465
SMILES=CN(C1=C(C=C(C=C1C(F)(F)F) [N+] (=O) [O-] ) [N+] (=O) [O-] )C2=C(C=C(C=C2Br)Br)Br
Section2= Chembox Properties
Formula=C14H7Br3F3N3O4
MolarMass=577.93 g/mol
Appearance=
Density=
MeltingPt=
BoilingPt=
Solubility=
Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=Bromethalin is a
rodenticide which poisons thecentral nervous system by uncouplingmitochondria loxidative phosphorylation , which causes a decrease inadenosine triphosphate (ATP) synthesis. Decreased ATP ultimately results in increasedintracranial pressure , which damagesneuronal axon s. This damage to the central nervous system can causeparalysis ,convulsion s, anddeath . [ [http://www.addl.purdue.edu/newsletters/1997/spring/bromoethalin.shtml Bromethalin] , Animal Disease Diagnostic Laboratory, Spring 1997 Newsletter]Risk of poisoning
There are no tests that will diagnose bromethalin poisoning in pets, but signs to watch for include severe muscle
tremor s,hyperexcitability , fits, extreme sensitivity to being touched (hyperesthesia ) andseizure s that appear to be caused by light or noise. Secondary bromethalin poisoning can occur in dogs or cats who eat a mouse killed by Bromethalin. In such cases, the pet owner may notice the "mild" symptoms such as loss of ability to bark, loss of appetite, depression, lethargy andcoma .There is no antidote for bromethalin, but symptoms can be treated with
corticosteroid s. Clinical studies indicate that symptoms return as soon as the corticosteroids are discontinued.References
Wikimedia Foundation. 2010.