Glycoside hydrolase family 1

Glycoside hydrolase family 1

Symbol = Glyco_hydro_1
Name = Glycosyl hydrolase family 1

width =
caption =
Pfam= PF00232
InterPro= IPR001360
SCOP = 1cbg
OPM family= 125
OPM protein= 1vff
PDB=PDB3|4pbgB:1-467 PDB3|3pbgB:1-467 PDB3|1pbgA:1-467PDB3|2pbgA:1-467 PDB3|1cbg :26-410 PDB3|1v02D:72-551PDB3|1v03A:72-551 PDB3|1v08B:74-558 PDB3|1e1fA:74-558PDB3|1hxjB:74-558 PDB3|1e4nB:74-558 PDB3|1e55B:74-558PDB3|1e4lA:74-558 PDB3|1e1eA:74-558 PDB3|1e56B:74-558PDB3|1h49A:74-558 PDB3|1e73M:21-222 PDB3|1e72M:21-222PDB3|1e4mM:21-222 PDB3|1e6sM:21-222 PDB3|1e6qM:21-222PDB3|1e70M:21-222 PDB3|1e6xM:21-222 PDB3|1e71M:21-222PDB3|1mquA:3-435 PDB3|1uz1A:2-444 PDB3|1oinA:2-444PDB3|1oimB:2-444 PDB3|1od0A:2-444 PDB3|1oifB:2-444PDB3|1w3jB:2-444 PDB3|1ug6A:1-431 PDB3|1np2A:1-431PDB3|1gonB:14-476 PDB3|1gnxB:14-476 PDB3|1bggC:2-444PDB3|1bgaA:2-444 PDB3|1tr1C:2-444 PDB3|1e4iA:2-444PDB3|1uyqA:2-444 PDB3|1qoxL:2-448 PDB3|1wcgA:1-464PDB3|1uwsA:308-471 PDB3|1uwrA:308-471 PDB3|1uwqB:308-471PDB3|1uwiA:308-471 PDB3|1uwuA:308-471 PDB3|1gowA:308-471PDB3|1uwtA:308-471 PDB3|1qvbA:307-470 PDB3|1vffA:1-408

Glycoside hydrolase family 1 is a family of glycoside hydrolases.

O-Glycosyl hydrolases EC number|3.2.1. are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different familiescite journal |author=Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G |title=Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue=15 |pages=7090–7094 |year=1995 |pmid=7624375 |doi=10.1073/pnas.92.15.7090] cite journal |author=Henrissat B, Davies G |title=Structures and mechanisms of glycosyl hydrolases |journal=Structure |volume=3 |issue=9 |pages=853–859 |year=1995 |pmid=8535779 |doi=10.1016/S0969-2126(01)00220-9] [ [ Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999.] ] . This classification is available on the CAZy(CArbohydrate-Active EnZymes) web site [ [ Henrissat, B. and Coutinho P.M. "Carbohydrate-Active Enzymes server". 1999.] ] . Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'.

Glycoside hydrolase family 1 [ CAZY GH_1] comprises enzymes with a number of known activities; beta-glucosidase (EC number|; beta-galactosidase (EC number|; 6-phospho-beta-galactosidase (EC number|; 6-phospho-beta-glucosidase (EC number|; lactase-phlorizin hydrolase (EC number|, lactase (EC number|; beta-mannosidase (EC number|; myrosinase (EC number|


*6-phospho-beta-galactosidase InterPro|IPR005928

Human proteins containing this domain


ee also

[ GH1 in CAZypedia]


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Glycoside hydrolase — Glycoside hydrolases (also called glycosidases) catalyze the hydrolysis of the glycosidic linkage to generate two smaller sugars. They are extremely common enzymes with roles in nature including degradation of biomass such as cellulose and… …   Wikipedia

  • Glycoside hydrolase — L alpha Amylase pancréatique 1HNY, une glycoside hydrolase Les Glycoside hydrolases (ou glycosidases) catalysent l hydrolyse de liaisons glycosidiques et libèrent au moins un composé osidique. Ce sont des enzymes extrêmement communes, dont les… …   Wikipédia en Français

  • Семейство GH97 — гликозил гидролаз Обозначения в базах данных Pfam PF10566 InterPro IPR019563 CAZy …   Википедия

  • Хитиназы — Хитиназа из семян ячменя Хитиназы (КФ  это ферменты, катализирующие деградацию …   Википедия

  • Хитиназа — Хитиназы (КФ это ферменты, катализирующие деградацию хитина, действующие наиболее часто как эндоферменты, отщепляя хитоолигосахариды длиной в 2 6 N ацетилглюкозаминовых остатков [1]. Хитиназы относятся к группе О гликозидных гидролаз,… …   Википедия

  • Семейство GH57 — гликозил гидролаз Обозначения в базах данных Pfam PF03065 InterPro IPR004300 CAZy …   Википедия

  • Lysozyme — single crystal Identifiers EC number …   Wikipedia

  • Neuraminidase — Neuraminic acid Neuraminidase enzymes are glycoside hydrolase enzymes (EC that cleave the glycosidic linkages of neuraminic acids. Neuraminidase enzymes are a large family, found in a range of organisms. The most commonly known… …   Wikipedia

  • Carbohydrate-binding module — CBM 1 three dimensional structures of three engineered cellulose binding domains of cellobiohydrolase i from trichoderma reesei, nmr, 18 structures Identifiers Symbol CBM 1 …   Wikipedia

  • List of gene families — This is a list of gene families or gene complexes, that is sets of genes which occur across a number of different species which often serve similar biological functions. These gene families typically encode functionally related proteins, and… …   Wikipedia