Sudan IV

Sudan IV
Sudan IV
Identifiers
CAS number 85-83-6
ChemSpider 11252033 YesY
KEGG C19520 YesY
Jmol-3D images Image 1
Properties
Molecular formula C24H20N4O
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Sudan IV (C24H20N4O) is a lysochrome (fat-soluble dye) diazo dye used for the staining of lipids, triglycerides and lipoproteins on frozen paraffin sections. It has the appearance of reddish brown crystals with melting point 199 °C and maximum absorption at 520(357) nm.

Sudan IV is one of the dyes used for Sudan staining. Similar dyes include Oil Red O, Sudan III, and Sudan Black B. Staining is an important biochemical technique, offering the ability to visually qualify the presence of the fatty compound of interest without isolating it. For staining purposes Sudan IV can be made up in propylene glycol[1]. Alternatively, authors have reported using the dye saturated in isopropyl alcohol, 95% ethanol, or 0.05% by weight in acetone:ethanol:water (50:35:15)[citation needed]. The idea is to use a moderately apolar solvent to solubilize the dye allowing it to partition into the highly apolar fat without the solvent solubilizing the fat to be stained.

Sudan I, Sudan III, and Sudan IV have been classified as category 3 carcinogens by the International Agency for Research on Cancer.[1]

In its purified form it is called Biebrich scarlet R, which should not be confused with the water-soluble Biebrich scarlet.

In industry, it is used to color nonpolar substances like oils, fats, waxes, greases, various hydrocarbon products, and acrylic emulsions. Sudan IV is also used in United Kingdom as a fuel dye to dye lower-taxed heating oil; because of that it is also known as Oil Tax Red. As a food dye, Sudan IV is considered an illegal dye, mainly because of its harmful effect over a long period of time, as it is a carcinogen. It was ruled unsafe in the 1995 food safety regulations report.

References

  1. ^ Refat NA, Ibrahim ZS, Moustafa GG, Sakamoto KQ, Ishizuka M, Fujita S (2008). "The induction of cytochrome P450 1A1 by sudan dyes". J. Biochem. Mol. Toxicol. 22 (2): 77–84. doi:10.1002/jbt.20220. PMID 18418879. 

External links


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См. также в других словарях:

  • Sudan 1 — Sudan® Farbstoffe sind synthetisch hergestellte Farbstoffe, wobei es sich bei den gelben, orangen und roten Typen um Azofarbstoffe, bei den blauen um Anthrachinonfarbstoffe und bei den grünen um Mischungen aus Azo und Anthrachinonfarbstoffen… …   Deutsch Wikipedia

  • Sudan IV — Sudan® Farbstoffe sind synthetisch hergestellte Farbstoffe, wobei es sich bei den gelben, orangen und roten Typen um Azofarbstoffe, bei den blauen um Anthrachinonfarbstoffe und bei den grünen um Mischungen aus Azo und Anthrachinonfarbstoffen… …   Deutsch Wikipedia

  • Sudan I — IUPAC name 1 phenylazonaphth 2 ol Identifiers …   Wikipedia

  • Sudan TV — Création 1962 Langue Arabe, anglais Pays   …   Wikipédia en Français

  • Sudan — Sudan, TX U.S. city in Texas Population (2000): 1039 Housing Units (2000): 460 Land area (2000): 0.907197 sq. miles (2.349629 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 0.907197 sq. miles (2.349629 sq. km)… …   StarDict's U.S. Gazetteer Places

  • Sudan, TX — U.S. city in Texas Population (2000): 1039 Housing Units (2000): 460 Land area (2000): 0.907197 sq. miles (2.349629 sq. km) Water area (2000): 0.000000 sq. miles (0.000000 sq. km) Total area (2000): 0.907197 sq. miles (2.349629 sq. km) FIPS code …   StarDict's U.S. Gazetteer Places

  • Sudân — (Beled es S., »Land der Schwarzen«, Nigritien), der Teil des Binnenlandes von Nordafrika (s. Karten »Ägypten« und »Guinea«), der vom 5.° nördl. Br. im W. bis zum 14.°, im O. bis zum 22.° nördl. Br. reicht, zwischen Sahara, Libyscher und Nubischer …   Meyers Großes Konversations-Lexikon

  • Sudan — • The Vicariate Apostolic of Sudan or Central Africa Catholic Encyclopedia. Kevin Knight. 2006 …   Catholic encyclopedia

  • Sudan — 1842, from Arabic Bilad al sudan, lit. country of the blacks, from sud, pl. of aswad (fem. sauda) black …   Etymology dictionary

  • Sudan — [so͞o dan′, so͞odän′] 1. vast semiarid region in NC Africa, south of the Sahara, extending from the Atlantic to the Red Sea 2. country in the E part of this region, south of Egypt: formerly a British & Egyptian condominium called ANGLO EGYPTIAN… …   English World dictionary


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