GPRC5A

GPRC5A

G protein-coupled receptor, family C, group 5, member A, also known as GPRC5A, is a human gene.cite web | title = Entrez Gene: GPRC5A G protein-coupled receptor, family C, group 5, member A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9052| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may play a role in embryonic development and epithelial cell differentiation.cite web | title = Entrez Gene: GPRC5A G protein-coupled receptor, family C, group 5, member A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9052| accessdate = ]

ee also

* Retinoic acid-inducible orphan G protein-coupled receptor

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Cafferata EG, Gonzalez-Guerrico AM, Pivetta OH, Santa-Coloma TA |title=Identification by differential display of a mRNA specifically induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in T84 human colon carcinoma cells. |journal=Cell. Mol. Biol. (Noisy-le-grand) |volume=42 |issue= 5 |pages= 797–804 |year= 1997 |pmid= 8832110 |doi=
*cite journal | author=Cheng Y, Lotan R |title=Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor. |journal=J. Biol. Chem. |volume=273 |issue= 52 |pages= 35008–15 |year= 1999 |pmid= 9857033 |doi=
*cite journal | author=Bräuner-Osborne H, Krogsgaard-Larsen P |title=Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain. |journal=Genomics |volume=65 |issue= 2 |pages= 121–8 |year= 2000 |pmid= 10783259 |doi= 10.1006/geno.2000.6164
*cite journal | author=Robbins MJ, Michalovich D, Hill J, "et al." |title=Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). |journal=Genomics |volume=67 |issue= 1 |pages= 8–18 |year= 2001 |pmid= 10945465 |doi= 10.1006/geno.2000.6226
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Tao Q, Cheng Y, Clifford J, Lotan R |title=Characterization of the murine orphan G-protein-coupled receptor gene Rai3 and its regulation by retinoic acid. |journal=Genomics |volume=83 |issue= 2 |pages= 270–80 |year= 2004 |pmid= 14706456 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wu Q, Ding W, Mirza A, "et al." |title=Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target. |journal=J. Biol. Chem. |volume=280 |issue= 13 |pages= 12935–43 |year= 2005 |pmid= 15659406 |doi= 10.1074/jbc.M409901200
*cite journal | author=Zhang Y, Wolf-Yadlin A, Ross PL, "et al." |title=Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. |journal=Mol. Cell Proteomics |volume=4 |issue= 9 |pages= 1240–50 |year= 2005 |pmid= 15951569 |doi= 10.1074/mcp.M500089-MCP200
*cite journal | author=Nousiainen M, Silljé HH, Sauer G, "et al." |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103
*cite journal | author=Hirano M, Zang L, Oka T, "et al." |title=Novel reciprocal regulation of cAMP signaling and apoptosis by orphan G-protein-coupled receptor GPRC5A gene expression. |journal=Biochem. Biophys. Res. Commun. |volume=351 |issue= 1 |pages= 185–91 |year= 2006 |pmid= 17055459 |doi= 10.1016/j.bbrc.2006.10.016

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  • Retinoic acid-inducible orphan G protein-coupled receptor — protein Name = G protein coupled receptor, family C, group 5, member A caption = width = HGNCid = 9836 Symbol = GPRC5A AltSymbols = RAIG1, RAI3 EntrezGene = 9052 OMIM = 604138 RefSeq = NM 003979 UniProt = Q8NFJ5 PDB = ECnumber = Chromosome = 12… …   Wikipedia

  • Class C GPCR — 7 transmembrane receptor (metabotropic glutamate family) Identifiers Symbol 7tm 3 Pfam PF00003 InterPro …   Wikipedia

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