Glucosamine-phosphate N-acetyltransferase

Glucosamine-phosphate N-acetyltransferase

In enzymology, a glucosamine-phosphate N-acetyltransferase (EC number|2.3.1.4) is an enzyme that catalyzes the chemical reaction

:acetyl-CoA + D-glucosamine 6-phosphate ightleftharpoons CoA + N-acetyl-D-glucosamine 6-phosphate

Thus, the two substrates of this enzyme are acetyl-CoA and D-glucosamine 6-phosphate, whereas its two products are CoA and N-acetyl-D-glucosamine 6-phosphate.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase. Other names in common use include phosphoglucosamine transacetylase, phosphoglucosamine acetylase, glucosamine-6-phosphate acetylase, D-glucosamine-6-P N-acetyltransferase, aminodeoxyglucosephosphate acetyltransferase, glucosamine 6-phosphate acetylase, glucosamine 6-phosphate N-acetyltransferase, N-acetylglucosamine-6-phosphate synthase, phosphoglucosamine N-acetylase, glucosamine-phosphate N-acetyltransferase, and glucosamine-6-phosphate N-acetyltransferase. This enzyme participates in glutamate metabolism and aminosugars metabolism.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1I12, PDB link|1I1D, PDB link|1I21, PDB link|2HUZ, and PDB link|2O28.

References

*
*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9031-91-8."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Look at other dictionaries:

  • glucosamine-phosphate N-acetyltransferase — glu·co·sa·mine phos·phate N ac·e·tyl·trans·fer·ase (gloo kōsґə mēn fosґfāt as″ə tēl transґfər ās) [EC 2.3.1.4] an enzyme of the transferase class that catalyzes the transfer of an acetyl group from… …   Medical dictionary

  • Glucosamine-1-phosphate N-acetyltransferase — In enzymology, a glucosamine 1 phosphate N acetyltransferase (EC number|2.3.1.157) is an enzyme that catalyzes the chemical reaction:acetyl CoA + alpha D glucosamine 1 phosphate ightleftharpoons CoA + N acetyl alpha D glucosamine 1 phosphateThus …   Wikipedia

  • N-acetyltransferase — is an enzyme that catalyzes the transfer of acetyl groups from acetyl CoA to arylamines.[1] They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.… …   Wikipedia

  • List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”