Carnitine O-acetyltransferase


Carnitine O-acetyltransferase

In enzymology, a carnitine O-acetyltransferase (EC number|2.3.1.7) is an enzyme that catalyzes the chemical reaction

:acetyl-CoA + carnitine ightleftharpoons CoA + O-acetylcarnitine

Thus, the two substrates of this enzyme are acetyl-CoA and carnitine, whereas its two products are CoA and O-acetylcarnitine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:carnitine O-acetyltransferase. Other names in common use include acetyl-CoA-carnitine O-acetyltransferase, acetylcarnitine transferase, carnitine acetyl coenzyme A transferase, carnitine acetylase, carnitine acetyltransferase, carnitine-acetyl-CoA transferase, and CATC. This enzyme participates in alanine and aspartate metabolism.

tructural studies

As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1NDB, PDB link|1NDF, PDB link|1NDI, PDB link|1NM8, PDB link|1S5O, PDB link|1T7O, and PDB link|1T7Q.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-90-7."

Gene Ontology (GO) codes


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