Formylmethionine deformylase

Formylmethionine deformylase

In enzymology, a formylmethionine deformylase (EC number|3.5.1.31) is an enzyme that catalyzes the chemical reaction

:N-formyl-L-methionine + H2O ightleftharpoons formate + L-methionine

Thus, the two substrates of this enzyme are N-formyl-L-methionine and H2O, whereas its two products are formate and L-methionine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-methionine amidohydrolase. This enzyme participates in methionine metabolism and glyoxylate and dicarboxylate metabolism.

tructural studies

As of late 2007, 14 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1BS4, PDB link|1BS5, PDB link|1BS6, PDB link|1BS7, PDB link|1BS8, PDB link|1BSZ, PDB link|1DEF, PDB link|1DFF, PDB link|1G27, PDB link|1G2A, PDB link|1ICJ, PDB link|1JYM, PDB link|1RL4, and PDB link|2DEF.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9032-86-4."

Gene Ontology (GO) codes


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