Agmatine deiminase


Agmatine deiminase

In enzymology, an agmatine deiminase (EC number|3.5.3.12) is an enzyme that catalyzes the chemical reaction

:agmatine + H2O ightleftharpoons N-carbamoylputrescine + NH3

Thus, the two substrates of this enzyme are agmatine and H2O, whereas its two products are N-carbamoylputrescine and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine iminohydrolase. This enzyme is also called agmatine amidinohydrolase. This enzyme participates in urea cycle and metabolism of amino groups.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1VKP, PDB link|2EWO, PDB link|2JER, and PDB link|2Q3U.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37289-17-1."

Gene Ontology (GO) codes


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