Biogenesis of lysosome-related organelles complex 1


Biogenesis of lysosome-related organelles complex 1

BLOC-1 or biogenesis of lysosome-related organelles complex 1 is a ubiquitously expressed multisubunit protein complex. BLOC-1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The complex was first described in 2004. cite journal |author=Falcón-Pérez JM, Starcevic M, Gautam R, Dell'Angelica EC |title=BLOC-1, a novel complex containing the pallidin and muted proteins involved in the biogenesis of melanosomes and platelet-dense granules |journal=J. Biol. Chem. |volume=277 |issue=31 |pages=28191–9 |year=2002 |pmid=12019270 |doi=10.1074/jbc.M204011200]

The identified protein subunits of BLOC-1 include:

* pallidin,
* muted (protein),
* dysbindin,
* cappuccino (protein)
* Snapin,
* BLOS1,
* BLOS2,
* BLOS3

References


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • BLOC1S2 — Biogenesis of lysosome related organelles complex 1, subunit 2, also known as BLOC1S2, is a human gene.cite web | title = Entrez Gene: BLOC1S2 biogenesis of lysosome related organelles complex 1, subunit 2| url =… …   Wikipedia

  • BLOC1S1 — Biogenesis of lysosome related organelles complex 1, subunit 1, also known as BLOC1S1, is a human gene.cite web | title = Entrez Gene: BLOC1S1 biogenesis of lysosome related organelles complex 1, subunit 1| url =… …   Wikipedia

  • MUTED — homolog (mouse) Identifiers Symbols MUTED; DKFZp686E2287; FLJ18427; MU External IDs …   Wikipedia

  • CNO (gene) — Cappuccino homolog (mouse), also known as CNO, is a human gene.cite web | title = Entrez Gene: CNO cappuccino homolog (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=55330| accessdate = ] PBB… …   Wikipedia

  • SNAPAP — SNAP associated protein, also known as SNAPAP, is a human gene.cite web | title = Entrez Gene: SNAPAP SNAP associated protein| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23557| accessdate = ] PBB… …   Wikipedia

  • PLDN — Pallidin homolog (mouse), also known as PLDN, is a human gene.cite web | title = Entrez Gene: PLDN pallidin homolog (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=26258| accessdate = ] PBB Summary… …   Wikipedia

  • HPS1 — Hermansky Pudlak syndrome 1, also known as HPS1, is a human gene.cite web | title = Entrez Gene: HPS1 Hermansky Pudlak syndrome 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3257| accessdate = ] PBB… …   Wikipedia

  • Dysbindin — Dystrobrevin binding protein 1 Identifiers Symbols DTNBP1; DBND; DKFZp564K192; FLJ30031; HPS7; MGC20210; My031; SDY External IDs …   Wikipedia

  • Hermansky-Pudlak-Syndrom — Klassifikation nach ICD 10 E70.3 Albinismus Hermansky Pudlak Syndrom …   Deutsch Wikipedia

  • HPS4 — Hermansky Pudlak syndrome 4, also known as HPS4, is a human gene.cite web | title = Entrez Gene: HPS4 Hermansky Pudlak syndrome 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=89781| accessdate = ] PBB… …   Wikipedia


Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.