Poly(3-hydroxybutyrate) depolymerase

Poly(3-hydroxybutyrate) depolymerase

In enzymology, a poly(3-hydroxybutyrate) depolymerase (EC number|3.1.1.75) is an enzyme that catalyzes the chemical reaction

:poly [(R)-3-hydroxybutanoate] n + H2O ightleftharpoons poly [(R)-3-hydroxybutanoate] n-x + poly [(R)-3-hydroxybutanoate] x; x ightleftharpoons 1-5

Thus, the two substrates of this enzyme are [poly [(R)-3-hydroxybutanoate] n] and H2O, whereas its two products are [poly [(R)-3-hydroxybutanoate] n-x] and [poly [(R)-3-hydroxybutanoate] x; x] .

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is poly [(R)-3-hydroxybutanoate] hydrolase. Other names in common use include PHB depolymerase, poly(3HB) depolymerase, poly [(R)-hydroxyalkanoic acid] depolymerase, poly(HA) depolymerase, poly(HASCL) depolymerase, and poly [(R)-3-hydroxybutyrate] hydrolase.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|2D80 and PDB link|2D81.

References

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External links

Gene Ontology (GO) codes


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