GPR156

GPR156

GPR156 (G protein-coupled receptor 156), is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily.cite web | title = Entrez Gene: GPR156 G protein-coupled receptor 156| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=165829| accessdate = ] By sequence homology, this gene was proposed as being a possible GABAB receptor subunit, however when expressed in cells alone or with other GABAB subunits, no response to GABAB ligands could be detected. Therefore the function of this protein remains to be elucidated.cite journal | author = Calver AR, Michalovich D, Testa TT, Robbins MJ, Jaillard C, Hill J, Szekeres PG, Charles KJ, Jourdain S, Holbrook JD, Boyfield I, Patel N, Medhurst AD, Pangalos MN | title = Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor | journal = Brain Res. Mol. Brain Res. | volume = 110 | issue = 2 | pages = 305–17 | year = 2003 | pmid = 12591167 | doi = 10.1016/S0169-328X(02)00662-9 | issn = ]

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References

Further reading

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*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Calver AR, Michalovich D, Testa TT, "et al." |title=Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor. |journal=Brain Res. Mol. Brain Res. |volume=110 |issue= 2 |pages= 305–17 |year= 2003 |pmid= 12591167 |doi=
*cite journal | author=Vassilatis DK, Hohmann JG, Zeng H, "et al." |title=The G protein-coupled receptor repertoires of human and mouse. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 8 |pages= 4903–8 |year= 2003 |pmid= 12679517 |doi= 10.1073/pnas.0230374100
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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  • Class C GPCR — 7 transmembrane receptor (metabotropic glutamate family) Identifiers Symbol 7tm 3 Pfam PF00003 InterPro …   Wikipedia

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