Mg2+-importing ATPase


Mg2+-importing ATPase
magnesium-importing ATPase
Identifiers
EC number 3.6.3.2
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a Mg2+-importing ATPase (EC 3.6.3.2) is an enzyme that catalyzes the chemical reaction

ATP + H2O + Mg2+out \rightleftharpoons ADP + phosphate + Mg2+in

The 3 substrates of this enzyme are ATP, H2O, and Mg2+, whereas its 3 products are ADP, phosphate, and Mg2+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Mg2+-importing).

The mgtA gene which encodes this enzyme is thought to be regulated by a magnesium responsive RNA element.[1]

References

  1. ^ Groisman EA, Cromie MJ, Shi Y, Latifi T (2006). "A Mg2+-responding RNA that controls the expression of a Mg2+ transporter.". Cold Spring Harb Symp Quant Biol 71: 251–8. doi:10.1101/sqb.2006.71.005. PMID 17381304.