Threonine aldolase


Threonine aldolase

protein
name=threonine aldolase 1 pseudogene
caption=


width=
HGNCid=18004
Symbol=THA1P
AltSymbols=
EntrezGene=390816
OMIM=
RefSeq=XM_372682
UniProt=
PDB=
ECnumber=
Chromosome=17
Arm=q
Band=25.3
LocusSupplementaryData=
In enzymology, a threonine aldolase (EC number|4.1.2.5) is an enzyme that catalyzes the chemical reaction

:L-threonine ightleftharpoons glycine + acetaldehyde

Hence, this enzyme has one substrate, L-threonine, and two products, glycine and acetaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-threonine acetaldehyde-lyase (glycine-forming). This enzyme is also called L-threonine acetaldehyde-lyase. This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1JG8, PDB link|1LW4, PDB link|1LW5, PDB link|1M6S, and PDB link|1SVV.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|62213-23-4."

Gene Ontology (GO) codes


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