Indolepyruvate decarboxylase

In enzymology, an indolepyruvate decarboxylase (EC number|4.1.1.74) is an enzyme that catalyzes the chemical reaction

:3-(indol-3-yl)pyruvate $ightleftharpoons$ 2-(indol-3-yl)acetaldehyde + CO₂

Hence, this enzyme has one substrate, 3-(indol-3-yl)pyruvate, and two products, 2-(indol-3-yl)acetaldehyde and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming] . Other names in common use include indol-3-yl-pyruvate carboxy-lyase, and 3-(indol-3-yl)pyruvate carboxy-lyase. This enzyme participates in tryptophan metabolism.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1OVM.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9074-92-4."

Gene Ontology (GO) codes