Hydroxymandelonitrile lyase


Hydroxymandelonitrile lyase

In enzymology, a hydroxymandelonitrile lyase (EC number|4.1.2.11) is an enzyme that catalyzes the chemical reaction

:(S)-4-hydroxymandelonitrile ightleftharpoons cyanide + 4-hydroxybenzaldehyde

Hence, this enzyme has one substrate, (S)-4-hydroxymandelonitrile, and two products, cyanide and 4-hydroxybenzaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-4-hydroxymandelonitrile 4-hydroxybenzaldehyde-lyase (cyanide-forming). Other names in common use include hydroxynitrile lyase, oxynitrilase, Sorghum hydroxynitrile lyase, and (S)-4-hydroxymandelonitrile hydroxybenzaldehyde-lyase. This enzyme participates in cyanoamino acid metabolism.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1GXS.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9075-38-1."

Gene Ontology (GO) codes


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