- Citrate (pro-3S)-lyase
citrate (pro-3S)-lyase Identifiers EC number 18.104.22.168 CAS number 9012-83-3 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles
- citrate acetate + oxaloacetate
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is citrate oxaloacetate-lyase (forming acetate from the pro-S carboxymethyl group of citrate). Other names in common use include citrase, citratase, citritase, citridesmolase, citrate aldolase, citric aldolase, citrate lyase, citrate oxaloacetate-lyase, and citrate oxaloacetate-lyase [(pro-3S)-CH2COO-->acetate]. This enzyme participates in citrate cycle (tca cycle) and two-component system - general.
- DAGLEY S, DAWES EA (1955). "Citridesmolase: its properties and mode of action". Biochim. Biophys. Acta. 17 (2): 177–84. doi:10.1016/0006-3002(55)90348-6. PMID 13239657.
- Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate". Eur. J. Biochem. 80 (2): 479–88. doi:10.1111/j.1432-1033.1977.tb11903.x. PMID 336371.
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