Selenocysteine lyase

Selenocysteine lyase

In enzymology, a selenocysteine lyase (EC number| is an enzyme that catalyzes the chemical reaction

:L-selenocysteine + reduced acceptor ightleftharpoons selenide + L-alanine + acceptor

Thus, the two substrates of this enzyme are L-selenocysteine and reduced acceptor, whereas its 3 products are selenide, L-alanine, and acceptor.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-selenocysteine selenide-lyase (L-alanine-forming). Other names in common use include selenocysteine reductase, and selenocysteine beta-lyase. This enzyme participates in selenoamino acid metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1I29, PDB link|1JF9, PDB link|1KMJ, and PDB link|1KMK.



External links

::"The CAS registry number for this enzyme class is CAS registry|82047-76-5."

Gene Ontology (GO) codes

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