1-aminocyclopropane-1-carboxylate synthase


1-aminocyclopropane-1-carboxylate synthase

In enzymology, a 1-aminocyclopropane-1-carboxylate synthase (EC number|4.4.1.14) is an enzyme that catalyzes the chemical reaction

:S-adenosyl-L-methionine ightleftharpoons 1-aminocyclopropane-1-carboxylate + methylthioadenosine

Hence, this enzyme has one substrate, S-adenosyl-L-methionine, and two products, 1-aminocyclopropane-1-carboxylate and methylthioadenosine.

This enzyme belongs to the family of lyases, specifically carbon-sulfur lyases. The systematic name of this enzyme class is S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming). Other names in common use include 1-aminocyclopropanecarboxylate synthase, 1-aminocyclopropane-1-carboxylic acid synthase, 1-aminocyclopropane-1-carboxylate synthetase, aminocyclopropanecarboxylic acid synthase, aminocyclopropanecarboxylate synthase, ACC synthase, and S-adenosyl-L-methionine methylthioadenosine-lyase. This enzyme participates in propanoate metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1B8G, PDB link|1IAX, PDB link|1IAY, PDB link|1M4N, PDB link|1M7Y, and PDB link|1YNU.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|72506-68-4."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • List of EC numbers (EC 4) — This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 4.1: Carbon Carbon LyasesEC… …   Wikipedia

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • Amino acid — This article is about the class of chemicals. For the structures and properties of the standard proteinogenic amino acids, see Proteinogenic amino acid. The generic structure of an alpha amino acid in its unionized form …   Wikipedia

  • SiRNA — Saltar a navegación, búsqueda Artículo principal: RNAi El nombre siRNA son las siglas en inglés de small interfering RNA, en español ARN pequeño de interferencia o ARN de silenciamiento. Es un tipo de ARN interferente con una longitud de 20 a 25… …   Wikipedia Español

  • siRNA — Artículo principal: RNAi El nombre siRNA son las siglas en inglés de small interfering RNA, en español ARN pequeño de interferencia o ARN de silenciamiento. Es un tipo de ARN interferente con una longitud de 20 a 25 nucleótidos que es altamente… …   Wikipedia Español