Phosphopentomutase


Phosphopentomutase

In enzymology, a phosphopentomutase (EC number|5.4.2.7) is an enzyme that catalyzes the chemical reaction

:alpha-D-ribose 1-phosphate ightleftharpoons D-ribose 5-phosphate

Hence, this enzyme has one substrate, alpha-D-ribose 1-phosphate, and one product, D-ribose 5-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is alpha-D-ribose 1,5-phosphomutase. Other names in common use include phosphodeoxyribomutase, deoxyribose phosphomutase, deoxyribomutase, phosphoribomutase, alpha-D-glucose-1,6-bisphosphate:deoxy-D-ribose-1-phosphate, phosphotransferase, and D-ribose 1,5-phosphomutase. This enzyme participates in pentose phosphate pathway and purine metabolism. It has 3 cofactors: D-ribose 1,5-bisphosphate, alpha-D-Glucose 1,6-bisphosphate, and 2-Deoxy-D-ribose 1,5-bisphosphate.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2I09.

References

*
*
* Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.

External links

::"The CAS registry number for this enzyme class is CAS registry|9026-77-1."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Look at other dictionaries:

  • List of EC numbers (EC 5) — This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. =EC 5.1: Epimerases and… …   Wikipedia

  • Glucose-1,6-bisphosphate synthase — is a type of enzyme called a phosphotransferase and is involved in mammalian starch and sucrose metabolism (KEGG, [http://www.brenda.uni koeln.de/php/result flat.php4?ecno=2.7.1.106 2.7.1.106] ). It catalyzes the transfer of a phosphate group… …   Wikipedia

  • PGM2 — Phosphoglucomutase 2, also known as PGM2, is a human gene.cite web | title = Entrez Gene: PGM2 phosphoglucomutase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=55276| accessdate = ] PBB Summary section… …   Wikipedia

  • ppm — Abbreviation for parts per million. * * * parts per million; permanent pacemaker; phosphopentomutase; physician practice management; pigmented pupillary membrane; posterior papillary muscle; pulse position modulated * * * ppm abbr parts per… …   Medical dictionary

  • PPM — • parts per million; • permanent pacemaker; • phosphopentomutase; • physician practice management; • pigmented pupillary membrane; • posterior papillary muscle; • pulse position modulated …   Dictionary of medical acronyms & abbreviations