Phosphoacetylglucosamine mutase


Phosphoacetylglucosamine mutase

In enzymology, a phosphoacetylglucosamine mutase (EC number|5.4.2.3) is an enzyme that catalyzes the chemical reaction

:N-acetyl-alpha-D-glucosamine 1-phosphate ightleftharpoons N-acetyl-D-glucosamine 6-phosphate

Hence, this enzyme has one substrate, N-acetyl-alpha-D-glucosamine 1-phosphate, and one product, N-acetyl-D-glucosamine 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is N-acetyl-alpha-D-glucosamine 1,6-phosphomutase. Other names in common use include acetylglucosamine phosphomutase, acetylglucosamine phosphomutase, acetylaminodeoxyglucose phosphomutase, phospho-N-acetylglucosamine mutase, and N-acetyl-D-glucosamine 1,6-phosphomutase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, N-Acetyl-D-glucosamine 1,6-bisphosphate.

tructural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1WJW, PDB link|2DKA, PDB link|2DKC, and PDB link|2DKD.

References

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* Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.
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External links

::"The CAS registry number for this enzyme class is CAS registry|9027-51-4."

Gene Ontology (GO) codes


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