N-acylglucosamine-6-phosphate 2-epimerase

N-acylglucosamine-6-phosphate 2-epimerase
N-acylglucosamine-6-phosphate 2-epimerase
Identifiers
EC number 5.1.3.9
CAS number 37318-35-7
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-acylglucosamine-6-phosphate 2-epimerase (EC 5.1.3.9) is an enzyme that catalyzes the chemical reaction

N-acyl-D-glucosamine 6-phosphate \rightleftharpoons N-acyl-D-mannosamine 6-phosphate

Hence, this enzyme has one substrate, N-acyl-D-glucosamine 6-phosphate, and one product, N-acyl-D-mannosamine 6-phosphate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is N-acyl-D-glucosamine-6-phosphate 2-epimerase. Other names in common use include acylglucosamine-6-phosphate 2-epimerase, and acylglucosamine phosphate 2-epimerase. This enzyme participates in aminosugars metabolism.

Structural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1Y0E and 1YXY.

References

  • Ghosh S and Roseman S (1965). "The sialic acids. IV. N-Acyl-D-glucosamine 6-phosphate 2-epimerase". J. Biol. Chem. 240: 1525–1530. PMID 14285487. 
This isomerase article is a stub. You can help Wikipedia by expanding it.