NOX1


NOX1
NADPH oxidase 1
Identifiers
Symbols NOX1; GP91-2; MOX1; NOH-1; NOH1
External IDs OMIM300225 MGI2450016 HomoloGene48495 GeneCards: NOX1 Gene
RNA expression pattern
PBB GE NOX1 206418 at tn.png
PBB GE NOX1 207217 s at tn.png
PBB GE NOX1 207380 x at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 27035 237038
Ensembl ENSG00000007952 ENSMUSG00000031257
UniProt Q9Y5S8 n/a
RefSeq (mRNA) NM_007052.4 NM_172203.1
RefSeq (protein) NP_008983.2 NP_757340.1
Location (UCSC) Chr X:
100.1 – 100.13 Mb
Chr X:
130.62 – 130.76 Mb
PubMed search [2] [3]

NADPH oxidase 1 is an enzyme that in humans is encoded by the NOX1 gene.[1]

NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene.[2]

References

  1. ^ Suh YA, Arnold RS, Lassegue B, Shi J, Xu X, Sorescu D, Chung AB, Griendling KK, Lambeth JD (Sep 1999). "Cell transformation by the superoxide-generating oxidase Mox1". Nature 401 (6748): 79–82. doi:10.1038/43459. PMID 10485709. 
  2. ^ "Entrez Gene: NOX1 NADPH oxidase 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27035. 

Further reading


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