CoB-CoM heterodisulfide reductase

CoB-CoM heterodisulfide reductase

In enzymology, a CoB---CoM heterodisulfide reductase (EC number|1.8.98.1) is an enzyme that catalyzes the chemical reaction

:coenzyme B + coenzyme M + methanophenazine ightleftharpoons N-{7- [(2-sulfoethyl)dithio] heptanoyl}-O3-phospho-L-threonine + dihydromethanophenazine

The 3 substrates of this enzyme are coenzyme B, coenzyme M, and methanophenazine, whereas its two products are [N-{7- [(2-sulfoethyl)dithio] heptanoyl}-O3-phospho-L-threonine] and dihydromethanophenazine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with other, known, acceptors. The systematic name of this enzyme class is coenzyme B:coenzyme M:methanophenazine oxidoreductase. Other names in common use include heterodisulfide reductase, and soluble heterodisulfide reductase. This enzyme participates in folate biosynthesis.

References

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External links

Gene Ontology (GO) codes


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