- 1-Pyrroline-5-carboxylate dehydrogenase
enzymology, a 1-pyrroline-5-carboxylate dehydrogenase (EC number|126.96.36.199) is an enzymethat catalyzes the chemical reaction
This enzyme belongs to the family of
oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ("S")-1-pyrroline-5-carboxylate:NAD+ oxidoreductase. Other names in common use include delta-1-pyrroline-5-carboxylate dehydrogenase, 1-pyrroline dehydrogenase, pyrroline-5-carboxylate dehydrogenase, pyrroline-5-carboxylic acid dehydrogenase, L-pyrroline-5-carboxylate-NAD+ oxidoreductase, and 1-pyrroline-5-carboxylate:NAD+ oxidoreductase. This enzyme participates in glutamate metabolismand arginine and proline metabolism.
As of late 2007, 14 structures have been solved for this class of enzymes, with PDB accession codes PDB link|2BHP, PDB link|2BHQ, PDB link|2BJA, PDB link|2BJK, PDB link|2EHQ, PDB link|2EHU, PDB link|2EII, PDB link|2EIT, PDB link|2EIW, PDB link|2EJ6, PDB link|2EJD, PDB link|2EJL, PDB link|2IY6, and PDB link|2J40.
CAS registry numberfor this enzyme class is CAS registry|9054-82-4."
Gene Ontology (GO) codes
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