NUP62


NUP62

Nucleoporin 62kDa, also known as NUP62, is a human gene.

PBB_Summary
section_title =
summary_text = The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.cite web | title = Entrez Gene: NUP62 nucleoporin 62kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23636| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Stoffler D, Fahrenkrog B, Aebi U |title=The nuclear pore complex: from molecular architecture to functional dynamics. |journal=Curr. Opin. Cell Biol. |volume=11 |issue= 3 |pages= 391–401 |year= 1999 |pmid= 10395558 |doi= 10.1016/S0955-0674(99)80055-6
*cite journal | author=Geetha T, Wooten MW |title=Structure and functional properties of the ubiquitin binding protein p62. |journal=FEBS Lett. |volume=512 |issue= 1-3 |pages= 19–24 |year= 2002 |pmid= 11852044 |doi=10.1016/S0014-5793(02)02286-X
*cite journal | author=Carmo-Fonseca M, Kern H, Hurt EC |title=Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization. |journal=Eur. J. Cell Biol. |volume=55 |issue= 1 |pages= 17–30 |year= 1991 |pmid= 1915414 |doi=
*cite journal | author=Paschal BM, Gerace L |title=Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62. |journal=J. Cell Biol. |volume=129 |issue= 4 |pages= 925–37 |year= 1995 |pmid= 7744965 |doi=10.1083/jcb.129.4.925
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8
*cite journal | author=Grote M, Kubitscheck U, Reichelt R, Peters R |title=Mapping of nucleoporins to the center of the nuclear pore complex by post-embedding immunogold electron microscopy. |journal=J. Cell. Sci. |volume=108 ( Pt 9) |issue= |pages= 2963–72 |year= 1996 |pmid= 8537436 |doi=
*cite journal | author=Guan T, Müller S, Klier G, "et al." |title=Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. |journal=Mol. Biol. Cell |volume=6 |issue= 11 |pages= 1591–603 |year= 1996 |pmid= 8589458 |doi=
*cite journal | author=Park I, Chung J, Walsh CT, "et al." |title=Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 26 |pages= 12338–42 |year= 1996 |pmid= 8618896 |doi=10.1073/pnas.92.26.12338
*cite journal | author=Joung I, Strominger JL, Shin J |title=Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 12 |pages= 5991–5 |year= 1996 |pmid= 8650207 |doi=10.1073/pnas.93.12.5991
*cite journal | author=Vadlamudi RK, Joung I, Strominger JL, Shin J |title=p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins. |journal=J. Biol. Chem. |volume=271 |issue= 34 |pages= 20235–7 |year= 1996 |pmid= 8702753 |doi=10.1074/jbc.271.34.20235
*cite journal | author=Hu T, Guan T, Gerace L |title=Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. |journal=J. Cell Biol. |volume=134 |issue= 3 |pages= 589–601 |year= 1996 |pmid= 8707840 |doi=10.1083/jcb.134.3.589
*cite journal | author=Bullock TL, Clarkson WD, Kent HM, Stewart M |title=The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2). |journal=J. Mol. Biol. |volume=260 |issue= 3 |pages= 422–31 |year= 1996 |pmid= 8757804 |doi=10.1006/jmbi.1996.0411
*cite journal | author=Percipalle P, Clarkson WD, Kent HM, "et al." |title=Molecular interactions between the importin alpha/beta heterodimer and proteins involved in vertebrate nuclear protein import. |journal=J. Mol. Biol. |volume=266 |issue= 4 |pages= 722–32 |year= 1997 |pmid= 9102465 |doi= 10.1006/jmbi.1996.0801
*cite journal | author=Yaseen NR, Blobel G |title=Cloning and characterization of human karyopherin beta3. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 9 |pages= 4451–6 |year= 1997 |pmid= 9114010 |doi=10.1073/pnas.94.9.4451
*cite journal | author=Yoshima T, Yura T, Yanagi H |title=The trimerization domain of human heat shock factor 2 is able to interact with nucleoporin p62. |journal=Biochem. Biophys. Res. Commun. |volume=240 |issue= 1 |pages= 228–33 |year= 1997 |pmid= 9367915 |doi= 10.1006/bbrc.1997.7662
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3
*cite journal | author=Kehlenbach RH, Dickmanns A, Kehlenbach A, "et al." |title=A role for RanBP1 in the release of CRM1 from the nuclear pore complex in a terminal step of nuclear export. |journal=J. Cell Biol. |volume=145 |issue= 4 |pages= 645–57 |year= 1999 |pmid= 10330396 |doi=10.1083/jcb.145.4.645
*cite journal | author=Sanz L, Sanchez P, Lallena MJ, "et al." |title=The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation. |journal=Embo J. |volume=18 |issue= 11 |pages= 3044–53 |year= 1999 |pmid= 10356400 |doi= 10.1093/emboj/18.11.3044
*cite journal | author=Rachubinski RA, Marcus SL, Capone JP |title=The p56(lck)-interacting protein p62 stimulates transcription via the SV40 enhancer. |journal=J. Biol. Chem. |volume=274 |issue= 26 |pages= 18278–84 |year= 1999 |pmid= 10373430 |doi=10.1074/jbc.274.26.18278

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