CDC20


CDC20

Cell division cycle 20 homolog ("S. cerevisiae"), also known as CDC20, is a human gene.

PBB_Summary
section_title =
summary_text = CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.cite web | title = Entrez Gene: CDC20 cell division cycle 20 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=991| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Weinstein J, Jacobsen FW, Hsu-Chen J, "et al." |title=A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4. |journal=Mol. Cell. Biol. |volume=14 |issue= 5 |pages= 3350–63 |year= 1994 |pmid= 7513050 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Weinstein J |title=Cell cycle-regulated expression, phosphorylation, and degradation of p55Cdc. A mammalian homolog of CDC20/Fizzy/slp1. |journal=J. Biol. Chem. |volume=272 |issue= 45 |pages= 28501–11 |year= 1997 |pmid= 9353311 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Kallio M, Weinstein J, Daum JR, "et al." |title=Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. |journal=J. Cell Biol. |volume=141 |issue= 6 |pages= 1393–406 |year= 1998 |pmid= 9628895 |doi=
*cite journal | author=Fang G, Yu H, Kirschner MW |title=The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation. |journal=Genes Dev. |volume=12 |issue= 12 |pages= 1871–83 |year= 1998 |pmid= 9637688 |doi=
*cite journal | author=Weinstein J, Karim J, Geschwind DH, "et al." |title=Genomic organization, 5' flanking enhancer region, and chromosomal assignment of the cell cycle gene, p55Cdc. |journal=Mol. Genet. Metab. |volume=64 |issue= 1 |pages= 52–7 |year= 1998 |pmid= 9682218 |doi= 10.1006/mgme.1998.2698
*cite journal | author=Fang G, Yu H, Kirschner MW |title=Direct binding of CDC20 protein family members activates the anaphase-promoting complex in mitosis and G1. |journal=Mol. Cell |volume=2 |issue= 2 |pages= 163–71 |year= 1998 |pmid= 9734353 |doi=
*cite journal | author=Wassmann K, Benezra R |title=Mad2 transiently associates with an APC/p55Cdc complex during mitosis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 19 |pages= 11193–8 |year= 1998 |pmid= 9736712 |doi=
*cite journal | author=Kramer ER, Gieffers C, Hölzl G, "et al." |title=Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family. |journal=Curr. Biol. |volume=8 |issue= 22 |pages= 1207–10 |year= 1999 |pmid= 9811605 |doi=
*cite journal | author=Cahill DP, da Costa LT, Carson-Walter EB, "et al." |title=Characterization of MAD2B and other mitotic spindle checkpoint genes. |journal=Genomics |volume=58 |issue= 2 |pages= 181–7 |year= 1999 |pmid= 10366450 |doi= 10.1006/geno.1999.5831
*cite journal | author=Farruggio DC, Townsley FM, Ruderman JV |title=Cdc20 associates with the kinase aurora2/Aik. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 13 |pages= 7306–11 |year= 1999 |pmid= 10377410 |doi=
*cite journal | author=Kotani S, Tanaka H, Yasuda H, Todokoro K |title=Regulation of APC activity by phosphorylation and regulatory factors. |journal=J. Cell Biol. |volume=146 |issue= 4 |pages= 791–800 |year= 1999 |pmid= 10459014 |doi=
*cite journal | author=Ohtoshi A, Maeda T, Higashi H, "et al." |title=Human p55(CDC)/Cdc20 associates with cyclin A and is phosphorylated by the cyclin A-Cdk2 complex. |journal=Biochem. Biophys. Res. Commun. |volume=268 |issue= 2 |pages= 530–4 |year= 2000 |pmid= 10679238 |doi= 10.1006/bbrc.2000.2167
*cite journal | author=Luo X, Fang G, Coldiron M, "et al." |title=Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20. |journal=Nat. Struct. Biol. |volume=7 |issue= 3 |pages= 224–9 |year= 2000 |pmid= 10700282 |doi= 10.1038/73338
*cite journal | author=Wu H, Lan Z, Li W, "et al." |title=p55CDC/hCDC20 is associated with BUBR1 and may be a downstream target of the spindle checkpoint kinase. |journal=Oncogene |volume=19 |issue= 40 |pages= 4557–62 |year= 2000 |pmid= 11030144 |doi= 10.1038/sj.onc.1203803
*cite journal | author=Skoufias DA, Andreassen PR, Lacroix FB, "et al." |title=Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 8 |pages= 4492–7 |year= 2001 |pmid= 11274370 |doi= 10.1073/pnas.081076898
*cite journal | author=Reimann JD, Freed E, Hsu JY, "et al." |title=Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. |journal=Cell |volume=105 |issue= 5 |pages= 645–55 |year= 2001 |pmid= 11389834 |doi=
*cite journal | author=Zhang Y, Lees E |title=Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation. |journal=Mol. Cell. Biol. |volume=21 |issue= 15 |pages= 5190–9 |year= 2001 |pmid= 11438673 |doi= 10.1128/MCB.21.15.5190-5199.2001
*cite journal | author=Chen J, Fang G |title=MAD2B is an inhibitor of the anaphase-promoting complex. |journal=Genes Dev. |volume=15 |issue= 14 |pages= 1765–70 |year= 2001 |pmid= 11459826 |doi= 10.1101/gad.898701

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