Cellobiose dehydrogenase (acceptor)


Cellobiose dehydrogenase (acceptor)

In enzymology, a cellobiose dehydrogenase (acceptor) (EC number|1.1.99.18) is an enzyme that catalyzes the chemical reaction

:cellobiose + acceptor ightleftharpoons cellobiono-1,5-lactone + reduced acceptor

Thus, the two substrates of this enzyme are cellobiose and acceptor, whereas its two products are cellobiono-1,5-lactone and reduced acceptor.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is cellobiose:acceptor 1-oxidoreductase. Other names in common use include cellobiose dehydrogenase, cellobiose oxidoreductase, Phanerochaete chrysosporium cellobiose oxidoreductase, CBOR, cellobiose oxidase, cellobiose:oxygen 1-oxidoreductase, CDH, and cellobiose:(acceptor) 1-oxidoreductase. It employs sometimes one cofactor, FAD, but in most cases both a heme and a FAD. It makes the enzyme to one of the more complex extracellulae oxidoreductases. It is produced by wood degrading organisms.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1NAA and PDB link|1PL3.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|54576-85-1."

Gene Ontology (GO) codes


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