(S)-canadine synthase

(S)-canadine synthase

In enzymology, a (S)-canadine synthase (EC number| is an enzyme that catalyzes the chemical reaction

:(S)-tetrahydrocolumbamine + NADPH + H+ + O2 ightleftharpoons (S)-canadine + NADP+ + 2 H2O

The 4 substrates of this enzyme are (S)-tetrahydrocolumbamine, NADPH, H+, and O2, whereas its 3 products are (S)-canadine, NADP+, and H2O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and the other dehydrogenated. The systematic name of this enzyme class is (S)-tetrahydrocolumbamine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming). Other names in common use include (S)-tetrahydroberberine synthase, and (S)-tetrahydrocolumbamine oxidase (methylenedioxy-bridge-forming). This enzyme participates in alkaloid biosynthesis i. It employs one cofactor, heme-thiolate(P-450).



External links

::"The CAS registry number for this enzyme class is CAS registry|114308-22-4."

Gene Ontology (GO) codes

Wikimedia Foundation. 2010.

Look at other dictionaries:

  • Synthase — ist ein veraltetes Benennungsmuster für Enzyme. Es wird für alle Enzymsorten benutzt, wenn betont werden soll, dass es sich um eine Enzymreaktion mit synthetischem (erzeugendem) Charakter handelt. Verwechslungsgefahr besteht mit Synthetase, einer …   Deutsch Wikipedia

  • Synthase — In biochemistry, a synthase is an enzyme which catalyzes a synthesis process.Following the EC number classification, they belong to the group of ligases, with lyases catalysing the reverse reaction. Examples * ATP synthase * Citrate synthase *… …   Wikipedia

  • Synthase — Une synthase est une enzyme appartenant à la classe des ligases. Cette enzyme forme et défait des liaisons. Certaines synthases peuvent utiliser de l ATP. Exemples ATP synthase Tryptophane synthase Thymidylate synthase Acide gras synthase Citrate …   Wikipédia en Français

  • synthase — noun Any enzyme that catalyzes the synthesis of a biological compound but, unlike synthetases, does not make use of ATP as a source of energy …   Wiktionary

  • synthase — Trivial name used in the Enzyme Commission Report for a lyase reaction going in the reverse direction (NTP independent). For individual synthases, see the specific names. SEE ALSO: synthetase. * * * syn·thase sin .thās, .thāz n any of various… …   Medical dictionary

  • Synthase — Syn|tha|se [Kurzw. aus ↑ Synthese u. ↑ ase], die; , n: 1) veraltetes Syn. für ↑ Ligase 2) nicht empfohlenes Syn. für ↑ Lyase …   Universal-Lexikon

  • synthase — syn·thase …   English syllables

  • synthase — ˈsinˌthās, āz noun ( s) Etymology: synthesis + ase : any of various enzymes that catalyze the synthesis of a substance without involving the breaking of a high energy phosphate bond (as in ATP) …   Useful english dictionary

  • ATP synthase — Molecular model of ATP synthase by X ray diffraction method ATP synthase (EC is an important enzyme that provides energy for the cell to use through the synthesis of adenosine triphosphate (ATP). ATP is the most commonly used energy… …   Wikipedia

  • Cystathionine beta synthase — Structure of human cystathionine beta synthase.[1] …   Wikipedia

  • ATP-Synthase — Bezeichner Gen Name(n) Fo, F1 …   Deutsch Wikipedia