ITPKB

Inositol 1,4,5-trisphosphate 3-kinase B, also known as ITPKB, is a human gene.

PBB_Summary
section_title =
summary_text = The protein encoded by this gene regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [cite web | title = Entrez Gene: ITPKB inositol 1,4,5-trisphosphate 3-kinase B| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3707| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Szlufcik K, Missiaen L, Parys JB, "et al." |title=Uncoupled IP3 receptor can function as a Ca2+-leak channel: cell biological and pathological consequences. |journal=Biol. Cell |volume=98 |issue= 1 |pages= 1–14 |year= 2006 |pmid= 16354157 |doi= 10.1042/BC20050031

PBB_Controls
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