Prosidol

Prosidol

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IUPAC_name = 1-(2-ethoxyethyl)-4-phenylpiperidin-4-yl propionate



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synonyms = Prosidol
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C = 18 | H = 27 | N = 1 | O = 3
molecular_weight = 305.42 g/mol
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Prosidol is an opioid analgesic that is an analogue of prodine. It was developed in Russia in the 1990s during research into the related drug pethidine. [Osipova NA, Novikov GA, Vetsheva MS, Prokhorov BM, Beresnev VA, Loseva NA, Zemskaia SIu, Smolina TA. First experience in the use of a new Russian narcotic analgesic prosidol in oncology. (Russian) "Anesteziologiia i Reanimatologiia". 1994 Jul-Aug;(4):53-7.]

Prosidol has seen some clinical use, but is still a relatively new drug and does not yet have an extensive history of use. It produces similar effects to other opioids, such as analgesia and sedation, along with side effects such as nausea, itching, vomiting and respiratory depression which may be harmful or fatal. [Osipova NA. The problem of opioid tolerance and dependence during clinical use thereof. (Russian) "Anesteziologiia i Reanimatologiia". 1996 Jul-Aug;(4):17-21.] [Abuzarova GR. Prosidol, an original Russian opioid, in the treatment of pain syndromes. (Russian) "Anesteziologiia i Reanimatologiia". 2001 Sep-Oct;(5):74-7.]

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