- 3-oxoacyl-(acyl-carrier-protein) reductase
enzymology, a 3-oxoacyl- [acyl-carrier-protein] reductase (EC number|22.214.171.124) is an enzymethat catalyzes the chemical reaction
:(3R)-3-hydroxyacyl- [acyl-carrier-protein] + NADP+ 3-oxoacyl- [acyl-carrier-protein] + NADPH + H+
This enzyme belongs to the family of
oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (3R)-3-hydroxyacyl- [acyl-carrier-protein] :NADP+ oxidoreductase. Other names in common use include beta-ketoacyl- [acyl-carrier protein] (ACP) reductase, beta-ketoacyl acyl carrier protein (ACP) reductase, beta-ketoacyl reductase, beta-ketoacyl thioester reductase, beta-ketoacyl-ACP reductase, beta-ketoacyl-acyl carrier protein reductase, 3-ketoacyl acyl carrier protein reductase, NADPH-specific 3-oxoacyl- [acylcarrier protein] reductase, and 3-oxoacyl- [ACP] reductase. This enzyme participates in fatty acid biosynthesisand polyunsaturated fatty acidbiosynthesis.
As of late 2007, 21 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1I01, PDB link|1O5I, PDB link|1Q7B, PDB link|1Q7C, PDB link|1ULS, PDB link|1UZL, PDB link|1UZM, PDB link|1UZN, PDB link|2A4K, PDB link|2B4Q, PDB link|2C07, PDB link|2FR0, PDB link|2FR1, PDB link|2NM0, PDB link|2NTN, PDB link|2P68, PDB link|2PFF, PDB link|2PH3, PDB link|2PNF, PDB link|2UVD, and PDB link|2Z5L.
CAS registry numberfor this enzyme class is CAS registry|37250-34-3."
Gene Ontology (GO) codes
Wikimedia Foundation. 2010.
Look at other dictionaries:
3-oxoacyl-(acyl-carrier-protein) reductase (NADH) — In enzymology, a 3 oxoacyl [acyl carrier protein] reductase (NADH) (EC number|126.96.36.199) is an enzyme that catalyzes the chemical reaction:(3R) 3 hydroxyacyl [acyl carrier protein] + NAD+ ightleftharpoons 3 oxoacyl [acyl carrier protein] + NADH + … Wikipedia
Β-Ketoacyl ACP reductase — (or 3 oxoacyl (acyl carrier protein) reductase) is an enzyme involved in fatty acid synthesis.ReferencesExternal links … Wikipedia
3-oxoacyl-ACP reductase — A part of the fatty acid synthase complex; an enzyme reversibly reacting 3 oxoacyl ACP (ACP = acyl carrier protein) with NADPH to form d 3 hydroxyacyl ACP and NADP+. SYN: β ketoacyl ACP reductase … Medical dictionary
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
List of EC numbers (EC 2) — This list contains a list of EC numbers for the second group, EC 2, transferases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 2.1: Transferring One… … Wikipedia
metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism … Universalium