Affective spectrum

Affective spectrum

The affective spectrum is a grouping of related psychiatric and medical disorders which may accompany bipolar, unipolar, and schizoaffective disorders at statistically higher rates than would normally be expected. These disorders are identified by a common positive response to the same types of pharmacologic treatments. They also aggregate strongly in families and may therefore share common heritable underlying physiologic anomalies. Affective spectrum disorders include:

* Attention-deficit hyperactivity disordercite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Bipolar disorder
* Body dysmorphic disorder
* Bulimia nervosacite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=] and other eating disorders
* Cataplexycite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Dysthymiacite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Fibromyalgiacite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* General anxiety disordercite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Hypersexuality
* Irritable Bowel Syndromecite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Impulse-control disorders
* Kleptomania
* Migrainecite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Major Depressive Disordercite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* NarcolepsyFact|date=February 2007
* Obsessive-compulsive disordercite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Panic disordercite journal |author=Hudson JI, Pope HG Jr. |title=Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology? |journal=Am J Psychiatry |volume=147 |issue=5 |pages=552–64 |year=1990 |pmid=11859906 |doi=] cite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Posttraumatic stress disordercite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Premenstrual dysphoric disordercite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]
* Social phobiacite journal |author=Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, Laird NM, Biebl W, Tsuang MT |title=Family study of affective spectrum disorder |journal=Arch Gen Psychiatry |volume=60 |issue=2 |pages=170–7 |year=1990 |pmid=12578434 |doi=]

The following may also be part of the spectrum accompanying affective disordersFact|date=February 2007.

* Chronic pain
* Intermittent explosive disorder
* Pathological gambling
* Personality disorder
* Pyromania
* Substance abuse and addiction (includes alcoholism)
* Trichotillomania

Also, there are now studies linking heart diseaseFact|date=February 2007.

Please note that many of the terms above overlap. The generally accepted definition of these terms can be found in the Diagnostic and Statistical Manual of Mental Disorders (DSM).

Footnotes

See also

* Affect
* Affective
* Emotion
* List of emotions
* Mood disorder
* Mood (affective) disorders
* Psychopathology


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