CSNK2A1

CSNK2A1

Casein kinase 2, alpha 1 polypeptide, also known as CSNK2A1, is a human gene.

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summary_text = Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [cite web | title = Entrez Gene: CSNK2A1 casein kinase 2, alpha 1 polypeptide| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1457| accessdate = ]

References

Further reading

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citations =
*cite journal | author=ole-MoiYoi OK |title=Casein kinase II in theileriosis. |journal=Science |volume=267 |issue= 5199 |pages= 834–6 |year= 1995 |pmid= 7846527 |doi=
*cite journal | author=Allende JE, Allende CC |title=Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation. |journal=FASEB J. |volume=9 |issue= 5 |pages= 313–23 |year= 1995 |pmid= 7896000 |doi=
*cite journal | author=Faust M, Montenarh M |title=Subcellular localization of protein kinase CK2. A key to its function? |journal=Cell Tissue Res. |volume=301 |issue= 3 |pages= 329–40 |year= 2001 |pmid= 10994779 |doi=

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  • Casein kinase 2 — The Casein kinase 2 (EC 2.7.11.1) is a serine/threonine selective protein kinase that is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell… …   Wikipedia

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