Zygote intrafallopian transfer


Zygote intrafallopian transfer

Zygote intrafallopian transfer (ZIFT) is an infertility treatment where a blockage in the fallopian tubes prevents the normal binding of sperm to the egg. Egg cells are removed from a woman's ovaries, and in vitro fertilised. The resulting zygote is placed into the fallopian tube by the use of laparoscopy. The procedure is a spin-off of the gamete intrafallopian transfer (GIFT) procedure. ZIFT has a succsess rate of 64.8% in all cases.

Procedure

It takes, on average, 5 weeks to complete a cycle of ZIFT. First, the woman must take a fertility medication to stimulate egg production in the ovaries. The doctor will monitor the growth of the ovarian follicles, and once they are mature, the woman will be injected with human chorionic gonadotropins (hCG). The eggs will be harvested approximately 36 hours later, usually by transvaginal ovum retrieval. After fertilization in the laboratory the resulting early embryos or zygotes are placed into the woman's fallopian tubes using a laparoscope.

Indications

ZIFT has been used in infertiltiy situations where at least one fallopian tube is normal and other treatments have failed. However, the need for two interventions and the fact that IVF results are equal or better (in 2004) leaves few if any indications for this intervention.

Controversies

ZIFT, like IVF, is considered controversialFact|date=July 2008. because it makes preimplantation genetic diagnosis (PGD) possible, allowing potential parents to select the genetic makeup of their child before it is ever even implanted. Despite fears about possible negative social implications of PGD (such as those depicted in the dystopian science fiction film "Gattaca"), PGD is still commonly practiced alongside ZIFT and IVF.Fact|date=July 2008.


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  • zygote intrafallopian transfer — zygote in·tra·fal·lo·pi·an transfer .in trə fə lō pē ən n a method of assisting reproduction in cases of infertility in which eggs are obtained from an ovary and fertilized with sperm in vitro and the resulting fertilized eggs are inserted into a …   Medical dictionary

  • zygote intrafallopian transfer — noun Date: 1986 a method of assisting reproduction in cases of infertility that is similar to gamete intrafallopian transfer but in which eggs are fertilized in vitro and some of the resulting fertilized eggs are inserted into a fallopian tube… …   New Collegiate Dictionary

  • Zygote intrafallopian transfer (ZIFT) — A technique in which a woman s egg is fertilized outside the body, then implanted in one of her fallopian tubes. This technique is one of the methods used to overcome infertility, the inability of couples to produce offspring on their own. First …   Medical dictionary

  • gamete intrafallopian transfer — gamete in·tra·fal·lo·pi·an transfer .in trə fə lō pē ən n a method of assisting reproduction in cases of infertility in which eggs are obtained from an ovary, mixed with sperm, and inserted into a fallopian tube by a laparoscope abbr. GIFT called …   Medical dictionary

  • Gamete intrafallopian transfer — (GIFT) is a tool of assisted reproductive technology against infertility. Eggs are removed from a woman s ovaries, and placed in one of the Fallopian tubes, along with the man s sperm. The technique, which was pioneered by endocrinologist Ricardo …   Wikipedia

  • Intrafallopian — A term meaning within the fallopian tube. There are two fallopian tubes in female mammals, including human females. These tubes are also called oviducts. They serve as passageways connecting the egg producing ovaries to the uterus (womb) in the… …   Medical dictionary

  • Zygote — Infobox Embryology Name = PAGENAME Latin = GraySubject = GrayPage = Caption = Caption2 = System = CarnegieStage = Days = 1 Precursor = GivesRiseTo = MeshName = MeshNumber = DorlandsPre = z 01 DorlandsSuf = 12871436 : For other meanings see Zygote …   Wikipedia

  • Embryo transfer — Intervention 8 cell embryo for transfer 3 days after fertilization MeSH …   Wikipedia

  • Cytoplasmic transfer — is an assisted reproductive technology (ART), fertility technique whereby cytoplasm from a donor egg is injected into an egg with compromised mitochondria. The resulting egg is then fertilized with sperm and implanted in a womb, usually that of… …   Wikipedia

  • ZIFT — Stands for zygote intrafallopian transfer, a method used to treat infertility in which an egg fertilized in vitro (outside the body) is placed into a woman s fallopian tube. This technique is one used to overcome infertility, the inability of… …   Medical dictionary


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