Orexin receptor


Orexin receptor
hypocretin (orexin) receptor 1
Identifiers
Symbol HCRTR1
Entrez 3061
HUGO 4848
OMIM 602392
RefSeq NM_001525
UniProt O43613
Other data
Locus Chr. 1 p33
hypocretin (orexin) receptor 2
Identifiers
Symbol HCRTR2
Entrez 3062
HUGO 4849
OMIM 602393
RefSeq NM_001526
UniProt O43614
Other data
Locus Chr. 6 p11-q11

The orexin receptor (also referred to as the hypocretin receptor) is a G-protein-coupled receptor that binds the neuropeptide hormone orexin. There are two variants, OX1 and OX2, each encoded by a different gene (HCRTR1, HCRTR2).[1]

References

  1. ^ Spinazzi R, Andreis PG, Rossi GP, Nussdorfer GG (2006). "Orexins in the regulation of the hypothalamic-pituitary-adrenal axis". Pharmacol. Rev. 58 (1): 46–57. doi:10.1124/pr.58.1.4. PMID 16507882. 

External links

Metabolites and
signaling molecules
Peptide
Miscellaneous
Class B: Secretin like Class C: Metabotropic
glutamate / pheromone Class F:
Frizzled / Smoothened B trdu: iter (nrpl/grfl/cytl/horl), csrc (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd; path (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)

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Look at other dictionaries:

  • Hypocretin (orexin) receptor 1 — Hypocretin (orexin) receptor 1, also known as HCRTR1, is a human gene.cite web | title = Entrez Gene: HCRTR1 hypocretin (orexin) receptor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3061| accessdate …   Wikipedia

  • Hypocretin (orexin) receptor 2 — Hypocretin (orexin) receptor 2, also known as HCRTR2, is a human gene.cite web | title = Entrez Gene: HCRTR2 hypocretin (orexin) receptor 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=3062| accessdate …   Wikipedia

  • Orexin-A — Orexin A, also known as Hypocretin 1, is a naturally occurring, highly excitatory, neuropeptide released by the hypothalamus. As a pharmaceutical drug, Orexin A is most commonly administered as a nasal spray. This drug counteracts intellectual… …   Wikipedia

  • Orexin — Prepro orexin Solution phase NMR structure of orexin A based on the PDB coordinates 1R02. Identifiers …   Wikipedia

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