Cymarin


Cymarin
Cymarin
Systematic (IUPAC) name
(3S,5S,8R,10S,13R,14S,17R)-5,14-dihydroxy-3-((2R,4S,5S,6R)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yloxy)-13-methyl-17-(5-oxo-2,5-dihydrofuran-3-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 508-77-0
ATC code C01AC03
PubChem CID 10504
UNII UK3LS8435E YesY
ChEMBL CHEMBL1651908 YesY
Synonyms Cymarine; K-Strophanthin-α; NSC 7522; Strophantin K; WV 90043a; k-Strophanthin-α
Chemical data
Formula C30H44O9 
Mol. mass 548.665 g/mol
SMILES eMolecules & PubChem
 YesY(what is this?)  (verify)

Cymarin (or cymarine) is a cardiac glycoside. Apocynum cannabinum used as a source of fiber by Native Americans and Apocynum venetum (Chinese: 羅布麻) used as a herbal tea in China both contain cymarin.[1] Cymarin is a cardiogenic toxin that causes cardiac arrhythmia in humans.[2] Cymarin is used in modern medicine in formulated pharmaceutical preparations used to treat a variety of tumors.[citation needed]

References

  1. ^ Edible and Medicinal plants of the West, Gregory L. Tilford, ISBN 0-87842-359-1
  2. ^ The Merck Index, 12th Edition, 2830