IUPAC_name = 2-dimethylaminoethyl 2-(4-chlorophenoxy)acetate

| C=12 | H=16 | Cl=1 | N=1 | O=3
molecular_weight = 257.713
metabolism =
excretion =
pregnancy_category =
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Centrophenoxine (also called Meclofenoxate, and formerly sold under the brand name Lucidril) is a drug used to treat the symptoms of senile dementia and Alzheimer's Disease. It is a compound of two biochemicals: "dimethylaminoethanol" (DMAE) and "parachlorophenoxyacetate" (pCPA). DMAE is a natural substance, found especially in fish, and also produced in the human brain. pCPA is a synthetic compound that resembles a variety of plant hormones called auxins.

Like DMAE, it is a to the neurotransmitter acetylcholine and may increase levels of this chemical in the CNS. It also increases cellular membrane phospholipids which is considered by some to be an important antiaging effect. It is clinically showed to improve memory, have aq mental stimulant effect, and general cognition.

It is also used off-label as a nootropic, often combined with a racetam drug such as piracetam. A typical nootropic dose is 250-3,000 mg taken in 1 or more doses.

=Side Effects & Contraindications=

Centrophenoxine is generally considered safe. However possible side effects may include nausea or mild dizziness. People with severely high blood pressure or convulsive disorders such as epilepsy should avoid Centrophenoxine. [1] Large doses may cause tight jaw clenching.


1. [http://www.worldhealth.net/p/aadr-centrophenoxine.html Centrophenoxine Page @ The American Academy of Anti-Aging Medicine]

External links

* [http://www.lef.org/prod_hp/abstracts/centrophenoxineabs.html Collection of Scientific Abstracts on Centrophenoxine]

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