Yerkes is a surname, and may refer to:

* Charles Yerkes (1837 – 1905), American financier
* Robert Yerkes (1876 – 1956), American psychologist, ethologist, and primatologist
* Steve Yerkes (1888 - 1971), American baseball player

Yerkes may also refer to:

* Yerkes Observatory, an astronomical observatory of the University of Chicago

Yerkes can also refer to a rare species found in the Michoacan mountains, central Mexico. Very little is known of this creature. Although the only sights of it have been around the Paricutin volcano, it's said to be distantly related to the Tasmanian Devil, mainly due to it's teeth and fierce smile. It's very unpredictable which makes it hard to find. Apples are it's main diet.

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