Survival of motor neuron


Survival of motor neuron

protein
Name=survival of motor neuron 1, telomeric
caption=


width=
HGNCid=11117
Symbol=SMN1
AltSymbols=SMA@, SMA
EntrezGene=6606
OMIM=600354
RefSeq=NM_000344
UniProt=Q16637
PDB=
ECnumber=
Chromosome=5
Arm=q
Band=13
LocusSupplementaryData=
protein
Name=survival of motor neuron 2, centromeric
caption=


width=
HGNCid=11118
Symbol=SMN2
AltSymbols=
EntrezGene=6607
OMIM=601627
RefSeq=NM_017411
UniProt=Q16637
PDB=
ECnumber=
Chromosome=5
Arm=q
Band=13
LocusSupplementaryData=

Survival of motor neuron is a protein associated with spinal muscular atrophy.

A 2004 study using high-throughput screening found indoprofen to increase production of the survival of motor neuron protein, suggesting it may provide insight into treatments for spinal muscular atrophies. [cite journal |author=Lunn MR, Root DE, Martino AM, "et al" |title=Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism |journal=Chem Biol |volume=11 |issue=11 |pages=1489–93 |year=2004 |pmid=15555999 |doi=10.1016/j.chembiol.2004.08.024]

ee also

* motor neuron
* SMN1

References

External links

*


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Look at other dictionaries:

  • Survival of motor neuron protein-interacting protein 1 — Survival of motor neuron protein interacting protein 1, also known as SIP1, is a human gene.cite web | title = Entrez Gene: SIP1 survival of motor neuron protein interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… …   Wikipedia

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